node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS41155.1 | lnt | MexAM1_META1p3418 | MexAM1_META1p3419 | Putative HlyC/CorC family of transporters with CBS domains; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Apolipoprotein N-acyltransferase, copper homeostasis protein; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | 0.771 |
ACS41155.1 | miaB | MexAM1_META1p3418 | MexAM1_META1p3415 | Putative HlyC/CorC family of transporters with CBS domains; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | tRNA modification enzyme MiaB, putative isopentenyl-adenosine A37 tRNA methylthiolase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.491 |
ACS41155.1 | ybeY | MexAM1_META1p3418 | MexAM1_META1p3417 | Putative HlyC/CorC family of transporters with CBS domains; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Putative metalloprotease; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.844 |
ACS41155.1 | ybeZ | MexAM1_META1p3418 | MexAM1_META1p3416 | Putative HlyC/CorC family of transporters with CBS domains; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Putative enzyme with nucleoside triphosphate hydrolase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.645 |
cdd | era | MexAM1_META1p3171 | MexAM1_META1p2275 | Cytidine deaminase (cytidine aminohydrolase); This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.839 |
cdd | ybeY | MexAM1_META1p3171 | MexAM1_META1p3417 | Cytidine deaminase (cytidine aminohydrolase); This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Putative metalloprotease; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.544 |
cdd | ybeZ | MexAM1_META1p3171 | MexAM1_META1p3416 | Cytidine deaminase (cytidine aminohydrolase); This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Putative enzyme with nucleoside triphosphate hydrolase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.555 |
cmk | era | MexAM1_META1p2119 | MexAM1_META1p2275 | Cytidine monophosphate (CMP) kinase; Function of strongly homologous gene; enzyme. | GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.425 |
cmk | rsfS | MexAM1_META1p2119 | MexAM1_META1p3075 | Cytidine monophosphate (CMP) kinase; Function of strongly homologous gene; enzyme. | Conserved hypothetical protein, Iojap family protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.524 |
cmk | ybeZ | MexAM1_META1p2119 | MexAM1_META1p3416 | Cytidine monophosphate (CMP) kinase; Function of strongly homologous gene; enzyme. | Putative enzyme with nucleoside triphosphate hydrolase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.639 |
era | cdd | MexAM1_META1p2275 | MexAM1_META1p3171 | GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Cytidine deaminase (cytidine aminohydrolase); This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.839 |
era | cmk | MexAM1_META1p2275 | MexAM1_META1p2119 | GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Cytidine monophosphate (CMP) kinase; Function of strongly homologous gene; enzyme. | 0.425 |
era | recO | MexAM1_META1p2275 | MexAM1_META1p0821 | GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.772 |
era | rsfS | MexAM1_META1p2275 | MexAM1_META1p3075 | GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Conserved hypothetical protein, Iojap family protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.452 |
era | ybeY | MexAM1_META1p2275 | MexAM1_META1p3417 | GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Putative metalloprotease; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.886 |
era | ybeZ | MexAM1_META1p2275 | MexAM1_META1p3416 | GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Putative enzyme with nucleoside triphosphate hydrolase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.565 |
lnt | ACS41155.1 | MexAM1_META1p3419 | MexAM1_META1p3418 | Apolipoprotein N-acyltransferase, copper homeostasis protein; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | Putative HlyC/CorC family of transporters with CBS domains; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.771 |
lnt | miaB | MexAM1_META1p3419 | MexAM1_META1p3415 | Apolipoprotein N-acyltransferase, copper homeostasis protein; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | tRNA modification enzyme MiaB, putative isopentenyl-adenosine A37 tRNA methylthiolase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.465 |
lnt | ybeY | MexAM1_META1p3419 | MexAM1_META1p3417 | Apolipoprotein N-acyltransferase, copper homeostasis protein; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | Putative metalloprotease; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.717 |
lnt | ybeZ | MexAM1_META1p3419 | MexAM1_META1p3416 | Apolipoprotein N-acyltransferase, copper homeostasis protein; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | Putative enzyme with nucleoside triphosphate hydrolase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.683 |