STRINGSTRING
lnt lnt lpxA lpxA lpxC lpxC ACS41155.1 ACS41155.1 kdsA kdsA lpxK lpxK bamA bamA ybeY ybeY pgsA pgsA ACS38757.1 ACS38757.1 ybeZ ybeZ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
lntApolipoprotein N-acyltransferase, copper homeostasis protein; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (567 aa)    
Predicted Functional Partners:
lpxA
Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.847
lpxC
UDP-3-O-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
 
   
 0.818
ACS41155.1
Putative HlyC/CorC family of transporters with CBS domains; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
   
 0.771
kdsA
3-deoxy-8-phosphooctulonate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the KdsA family.
      
 0.747
lpxK
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
      
 0.747
bamA
Putative outer membrane protein assembly factor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
 
   
 0.745
ybeY
Putative metalloprotease; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
     
 0.717
pgsA
Phosphatidylglycerophosphate synthetase; Function of strongly homologous gene; enzyme; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
   
 0.715
ACS38757.1
Putative Lipoprotein releasing system, transmembrane protein, LolC/E family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
   
 0.692
ybeZ
Putative enzyme with nucleoside triphosphate hydrolase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
   
 0.683
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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