STRINGSTRING
ACS41181.1 ACS41181.1 rpsP rpsP rplU rplU rpmA rpmA rpsL rpsL rpsG rpsG rpmJ rpmJ rplD rplD rplM rplM rplQ rplQ rplX rplX
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
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Textmining
[Homology]
Score
ACS41181.1Class I peptide chain release factor domain; Function of strongly homologous gene; enzyme. (140 aa)    
Predicted Functional Partners:
rpsP
Ribosomal protein S16; Function of strongly homologous gene; structure; Belongs to the bacterial ribosomal protein bS16 family.
 
 
 0.943
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
   0.939
rpmA
50S ribosomal protein L27; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the bacterial ribosomal protein bL27 family.
   
 
 0.936
rpsL
30S ribosomal subunit protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
  
 
 0.902
rpsG
30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
  
 
 0.890
rpmJ
50S ribosomal protein L36; Function of strongly homologous gene; structure; Belongs to the bacterial ribosomal protein bL36 family.
   
 
 0.879
rplD
50S ribosomal subunit protein L4, regulates expression of S10 operon; Forms part of the polypeptide exit tunnel.
   
 
 0.875
rplM
50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
   0.862
rplQ
50S ribosomal subunit protein L17; Function of homologous gene experimentally demonstrated in an other organism; structure.
   
   0.851
rplX
50S ribosomal subunit protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
   
   0.844
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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