node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS41246.1 | murJ | MexAM1_META1p3510 | MexAM1_META1p3511 | Haloacid dehalogenase, type II; Function of strongly homologous gene; enzyme. | Putative peptidoglycan lipid II flippase protein, MurJ (MviN)-like protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.655 |
ftsI | mraY | MexAM1_META1p5088 | MexAM1_META1p5085 | Peptidoglycan glycosyltransferase (penicillin-binding protein); Function of strongly homologous gene; enzyme. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.917 |
ftsI | murA | MexAM1_META1p5088 | MexAM1_META1p1964 | Peptidoglycan glycosyltransferase (penicillin-binding protein); Function of strongly homologous gene; enzyme. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.711 |
ftsI | murJ | MexAM1_META1p5088 | MexAM1_META1p3511 | Peptidoglycan glycosyltransferase (penicillin-binding protein); Function of strongly homologous gene; enzyme. | Putative peptidoglycan lipid II flippase protein, MurJ (MviN)-like protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.565 |
ftsI | rpoD | MexAM1_META1p5088 | MexAM1_META1p0435 | Peptidoglycan glycosyltransferase (penicillin-binding protein); Function of strongly homologous gene; enzyme. | Sigma D (sigma 70) factor of RNA polymerase; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.582 |
lnt | lspA-2 | MexAM1_META1p3419 | MexAM1_META1p2600 | Apolipoprotein N-acyltransferase, copper homeostasis protein; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | Putative prolipoprotein signal peptidase (SPase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.426 |
lnt | murJ | MexAM1_META1p3419 | MexAM1_META1p3511 | Apolipoprotein N-acyltransferase, copper homeostasis protein; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | Putative peptidoglycan lipid II flippase protein, MurJ (MviN)-like protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.557 |
lnt | tolQ | MexAM1_META1p3419 | MexAM1_META1p5219 | Apolipoprotein N-acyltransferase, copper homeostasis protein; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | Membrane spanning protein in TolA-TolQ-TolR complex; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.665 |
lspA-2 | lnt | MexAM1_META1p2600 | MexAM1_META1p3419 | Putative prolipoprotein signal peptidase (SPase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | Apolipoprotein N-acyltransferase, copper homeostasis protein; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | 0.426 |
lspA-2 | mraY | MexAM1_META1p2600 | MexAM1_META1p5085 | Putative prolipoprotein signal peptidase (SPase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.416 |
lspA-2 | murJ | MexAM1_META1p2600 | MexAM1_META1p3511 | Putative prolipoprotein signal peptidase (SPase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | Putative peptidoglycan lipid II flippase protein, MurJ (MviN)-like protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.634 |
mraY | ftsI | MexAM1_META1p5085 | MexAM1_META1p5088 | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Peptidoglycan glycosyltransferase (penicillin-binding protein); Function of strongly homologous gene; enzyme. | 0.917 |
mraY | lspA-2 | MexAM1_META1p5085 | MexAM1_META1p2600 | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Putative prolipoprotein signal peptidase (SPase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.416 |
mraY | murA | MexAM1_META1p5085 | MexAM1_META1p1964 | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.813 |
mraY | murJ | MexAM1_META1p5085 | MexAM1_META1p3511 | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Putative peptidoglycan lipid II flippase protein, MurJ (MviN)-like protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.597 |
mraY | rpoD | MexAM1_META1p5085 | MexAM1_META1p0435 | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Sigma D (sigma 70) factor of RNA polymerase; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.410 |
mraY | tolQ | MexAM1_META1p5085 | MexAM1_META1p5219 | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Membrane spanning protein in TolA-TolQ-TolR complex; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.582 |
murA | ftsI | MexAM1_META1p1964 | MexAM1_META1p5088 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | Peptidoglycan glycosyltransferase (penicillin-binding protein); Function of strongly homologous gene; enzyme. | 0.711 |
murA | mraY | MexAM1_META1p1964 | MexAM1_META1p5085 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.813 |
murA | murJ | MexAM1_META1p1964 | MexAM1_META1p3511 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | Putative peptidoglycan lipid II flippase protein, MurJ (MviN)-like protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.593 |