STRINGSTRING
dprA dprA ACS38159.1 ACS38159.1 ACS39639.1 ACS39639.1 topA topA ACS42735.1 ACS42735.1 pyrB pyrB ACS38013.1 ACS38013.1 ACS38015.1 ACS38015.1 ACS42259.1 ACS42259.1 plsY plsY radC radC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dprADNA protecting protein DprA; Function of strongly homologous gene; factor. (397 aa)    
Predicted Functional Partners:
ACS38159.1
Putative phosphoribosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
 
 
 0.940
ACS39639.1
Island insertion determinant, chelatase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 0.925
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 0.897
ACS42735.1
Conserved membrane hypothetical protein; Homologs of previously reported genes of unknown function.
 
  
 0.897
pyrB
Aspartate carbamoyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
      0.888
ACS38013.1
Putative prepilin peptidase (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase A24 family.
  
  
 0.850
ACS38015.1
General secretion pathway protein E, ATPase component; Function of strongly homologous gene; putative enzyme.
 
  
 0.759
ACS42259.1
Putative transcriptional regulator, MarR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
   
    0.753
plsY
Putative 1-acyl glycerol-3-phosphate synthetase (PlsY); Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
 
     0.749
radC
DNA repair protein RadC; Function of strongly homologous gene; cell process; Belongs to the UPF0758 family.
  
  
 0.716
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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