STRINGSTRING
metY-3 metY-3 metAS metAS metX metX ACS41315.1 ACS41315.1 ACS42087.1 ACS42087.1 metH metH metC metC ACS40808.1 ACS40808.1 ahcY ahcY ACS40233.1 ACS40233.1 hom hom
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
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metY-3Trans-sulfuration enzyme (O-acetylhomoserine aminocarboxypropyltransferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (440 aa)    
Predicted Functional Partners:
metAS
Putative homoserine O-succinyltransferase (metA); Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.
 
 
 0.974
metX
Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
 
 0.960
ACS41315.1
Putative homoserine O-acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the AB hydrolase superfamily. MetX family.
 
 
 0.951
ACS42087.1
Putative hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.951
metH
B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.946
metC
Cystathionine beta-lyase, PLP-dependent (beta-cystathionase); Function of strongly homologous gene; enzyme.
 
 
0.938
ACS40808.1
Putative cystathionine gamma-synthase, PLP-dependent (metB); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
 
 
0.935
ahcY
S-adenosyl L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
 0.912
ACS40233.1
CoA Binding Domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
      0.859
hom
Homoserine dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.849
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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