node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS38723.1 | cobF | MexAM1_META1p0800 | MexAM1_META1p3613 | Putative cobalamin biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | 0.864 |
ACS38723.1 | cobH | MexAM1_META1p0800 | MexAM1_META1p1326 | Putative cobalamin biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Precorrin-8X methylmutase (Precorrin isomerase) (HBA synthase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.902 |
ACS38723.1 | cobI | MexAM1_META1p0800 | MexAM1_META1p1325 | Putative cobalamin biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Precorrin-2/cobalt-factor-2 C20-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the precorrin methyltransferase family. | 0.895 |
ACS38723.1 | cobJ | MexAM1_META1p0800 | MexAM1_META1p1324 | Putative cobalamin biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Precorrin-3B C(17)-methyltransferase (Precorrin-3 methyltransferase) (Precorrin-3 methylase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.900 |
ACS38723.1 | cobK | MexAM1_META1p0800 | MexAM1_META1p5173 | Putative cobalamin biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Precorrin-6A reductase (Precorrin-6X reductase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.913 |
ACS38723.1 | cobL | MexAM1_META1p0800 | MexAM1_META1p0799 | Putative cobalamin biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Precorrin-6Y C5,15-methyltransferase (decarboxylating); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.987 |
ACS38723.1 | cobM | MexAM1_META1p0800 | MexAM1_META1p0804 | Putative cobalamin biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Precorrin-4 C(11)-methyltransferase (Precorrin-3 methylase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the precorrin methyltransferase family. | 0.990 |
ACS38723.1 | cobQ | MexAM1_META1p0800 | MexAM1_META1p5174 | Putative cobalamin biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.693 |
ACS38723.1 | cobT | MexAM1_META1p0800 | MexAM1_META1p0682 | Putative cobalamin biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.603 |
cobF | ACS38723.1 | MexAM1_META1p3613 | MexAM1_META1p0800 | Precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | Putative cobalamin biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.864 |
cobF | cobG | MexAM1_META1p3613 | MexAM1_META1p1327 | Precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | precorrin-3B synthase; Function of strongly homologous gene; enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.900 |
cobF | cobH | MexAM1_META1p3613 | MexAM1_META1p1326 | Precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | Precorrin-8X methylmutase (Precorrin isomerase) (HBA synthase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.962 |
cobF | cobI | MexAM1_META1p3613 | MexAM1_META1p1325 | Precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | Precorrin-2/cobalt-factor-2 C20-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the precorrin methyltransferase family. | 0.823 |
cobF | cobJ | MexAM1_META1p3613 | MexAM1_META1p1324 | Precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | Precorrin-3B C(17)-methyltransferase (Precorrin-3 methyltransferase) (Precorrin-3 methylase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.960 |
cobF | cobK | MexAM1_META1p3613 | MexAM1_META1p5173 | Precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | Precorrin-6A reductase (Precorrin-6X reductase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.996 |
cobF | cobL | MexAM1_META1p3613 | MexAM1_META1p0799 | Precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | Precorrin-6Y C5,15-methyltransferase (decarboxylating); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.970 |
cobF | cobM | MexAM1_META1p3613 | MexAM1_META1p0804 | Precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | Precorrin-4 C(11)-methyltransferase (Precorrin-3 methylase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the precorrin methyltransferase family. | 0.993 |
cobF | cobQ | MexAM1_META1p3613 | MexAM1_META1p5174 | Precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.856 |
cobF | cobT | MexAM1_META1p3613 | MexAM1_META1p0682 | Precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.774 |
cobG | cobF | MexAM1_META1p1327 | MexAM1_META1p3613 | precorrin-3B synthase; Function of strongly homologous gene; enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | 0.900 |