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aldA aldA acs acs ackA ackA ackA-2 ackA-2 ackA-3 ackA-3 ACS42486.1 ACS42486.1 ACS41497.1 ACS41497.1 mxaF mxaF acyP acyP poxB poxB exa exa
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
aldAAldehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (507 aa)    
Predicted Functional Partners:
acs
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.966
ackA
Putative acetate kinase (ackA); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
 
 
 0.956
ackA-2
Putative acetate kinase, propionate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
 
 
 0.956
ackA-3
Putative acetate kinase (fragment); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
 
 
 0.956
ACS42486.1
Putative acetyl-coenzyme A synthetase (acsA-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
  
 0.953
ACS41497.1
Putative Zn-containing alcohol dehydrogenase (adh); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.932
mxaF
Methanol dehydrogenase subunit 1 precursor (MDH large alpha subunit) (MEDH); Catalyzes the oxidation of primary alcohols including methanol; Belongs to the bacterial PQQ dehydrogenase family.
   
 
 0.921
acyP
Acylphosphatase (Acylphosphate phosphohydrolase); Function of strongly homologous gene; enzyme.
    
 0.919
poxB
poxB; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TPP enzyme family.
 
 0.917
exa
Quinoprotein ethanol dehydrogenase precursor (QEDH); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.903
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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