STRINGSTRING
rrmJ rrmJ rpmD rpmD ftsH ftsH rpsA rpsA miaA miaA ACS40887.1 ACS40887.1 rsmB rsmB rplJ rplJ ACS42503.1 ACS42503.1 rplC rplC grpE grpE
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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rrmJRibosomal RNA large subunit methyltransferase E; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (239 aa)    
Predicted Functional Partners:
rpmD
50S ribosomal subunit protein L30; Function of strongly homologous gene; structure.
   
 
 0.926
ftsH
Cell division protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
 
  
 0.876
rpsA
30S ribosomal subunit protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
  
 0.859
miaA
Delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
   
  
 0.830
ACS40887.1
Putative SUN-family protein, RNA methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
 
 0.806
rsmB
16S rRNA m5C967 methyltransferase, S-adenosyl-L-methionine-dependent; Function of strongly homologous gene; enzyme; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
 
 0.801
rplJ
50S ribosomal subunit protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
   
 
 0.785
ACS42503.1
Putative ATP-independent RNA helicase, DEAD/DEAH-box family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the DEAD box helicase family.
  
 0.782
rplC
50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
  
 
 0.769
grpE
Putative heat shock protein (HSP-70 COFACTOR), grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction c [...]
  
    0.762
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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