STRINGSTRING
ACS41572.1 ACS41572.1 metH metH metK metK ACS41089.1 ACS41089.1 pdhB pdhB ACS42480.1 ACS42480.1 ACS40792.1 ACS40792.1 ACS39475.1 ACS39475.1 ACS41454.1 ACS41454.1 ACS39000.1 ACS39000.1 ACS42239.1 ACS42239.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS41572.1Hypothetical protein; No homology to any previously reported sequences. (172 aa)    
Predicted Functional Partners:
metH
B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
  0.900
metK
Methionine adenosyltransferase 1 (AdoMet synthetase); Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
     
  0.900
ACS41089.1
Putative hybrid histidine kinase with PAS/PAC and response regulator receiver domains; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
 
 0.867
pdhB
Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
    
 0.866
ACS42480.1
Putative PAS sensor hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.
 
 
 0.860
ACS40792.1
Putative sensor hybrid histidine kinase with two PAS and two response regulator receiver domains; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
 
 0.830
ACS39475.1
Hypothetical protein; No homology to any previously reported sequences.
 
 
 0.816
ACS41454.1
Putative sensor protein gacS (Synonyms : lemA); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.807
ACS39000.1
Putative multi-sensor hybrid histidine kinase/response regulator; Gene remnant; putative regulator.
 
      0.769
ACS42239.1
Putative hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.749
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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