node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS39408.1 | ACS41773.1 | MexAM1_META1p1546 | MexAM1_META1p4120 | Putative Sarcosine oxidase alpha subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Iron-sulphur Rieske protein; Function of strongly homologous gene; enzyme. | 0.848 |
ACS39408.1 | gcvP | MexAM1_META1p1546 | MexAM1_META1p0620 | Putative Sarcosine oxidase alpha subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Glycine dehydrogenase / decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.973 |
ACS39408.1 | glyA | MexAM1_META1p1546 | MexAM1_META1p3384 | Putative Sarcosine oxidase alpha subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.778 |
ACS39408.1 | soxB | MexAM1_META1p1546 | MexAM1_META1p1548 | Putative Sarcosine oxidase alpha subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Sarcosine oxidase beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.998 |
ACS39408.1 | soxB-3 | MexAM1_META1p1546 | MexAM1_META1p4108 | Putative Sarcosine oxidase alpha subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Sarcosine oxidase, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.967 |
ACS39408.1 | soxD-2 | MexAM1_META1p1546 | MexAM1_META1p4109 | Putative Sarcosine oxidase alpha subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Sarcosine oxidase, delta subunit; Function of strongly homologous gene; enzyme. | 0.997 |
ACS39408.1 | soxG | MexAM1_META1p1546 | MexAM1_META1p1545 | Putative Sarcosine oxidase alpha subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Sarcosine oxidase, gamma subunit; Function of strongly homologous gene; enzyme. | 0.999 |
ACS39408.1 | soxG-2 | MexAM1_META1p1546 | MexAM1_META1p4111 | Putative Sarcosine oxidase alpha subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Sarcosine oxidase, gamma subunit; Function of strongly homologous gene; enzyme. | 0.965 |
ACS41773.1 | ACS39408.1 | MexAM1_META1p4120 | MexAM1_META1p1546 | Iron-sulphur Rieske protein; Function of strongly homologous gene; enzyme. | Putative Sarcosine oxidase alpha subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.848 |
ACS41773.1 | soxA-2 | MexAM1_META1p4120 | MexAM1_META1p4110 | Iron-sulphur Rieske protein; Function of strongly homologous gene; enzyme. | Sarcosine oxidase, alpha subunit; Function of strongly homologous gene; enzyme. | 0.868 |
ACS41773.1 | soxB | MexAM1_META1p4120 | MexAM1_META1p1548 | Iron-sulphur Rieske protein; Function of strongly homologous gene; enzyme. | Sarcosine oxidase beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.709 |
ACS41773.1 | soxB-3 | MexAM1_META1p4120 | MexAM1_META1p4108 | Iron-sulphur Rieske protein; Function of strongly homologous gene; enzyme. | Sarcosine oxidase, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.755 |
ACS41773.1 | soxD-2 | MexAM1_META1p4120 | MexAM1_META1p4109 | Iron-sulphur Rieske protein; Function of strongly homologous gene; enzyme. | Sarcosine oxidase, delta subunit; Function of strongly homologous gene; enzyme. | 0.946 |
ACS41773.1 | soxG | MexAM1_META1p4120 | MexAM1_META1p1545 | Iron-sulphur Rieske protein; Function of strongly homologous gene; enzyme. | Sarcosine oxidase, gamma subunit; Function of strongly homologous gene; enzyme. | 0.868 |
ACS41773.1 | soxG-2 | MexAM1_META1p4120 | MexAM1_META1p4111 | Iron-sulphur Rieske protein; Function of strongly homologous gene; enzyme. | Sarcosine oxidase, gamma subunit; Function of strongly homologous gene; enzyme. | 0.905 |
gcvP | ACS39408.1 | MexAM1_META1p0620 | MexAM1_META1p1546 | Glycine dehydrogenase / decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Putative Sarcosine oxidase alpha subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.973 |
gcvP | glyA | MexAM1_META1p0620 | MexAM1_META1p3384 | Glycine dehydrogenase / decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.997 |
gcvP | ltaE | MexAM1_META1p0620 | MexAM1_META1p3334 | Glycine dehydrogenase / decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Low-specificity L-threonine aldolase (Low-specificity L- TA); Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 0.946 |
gcvP | soxA-2 | MexAM1_META1p0620 | MexAM1_META1p4110 | Glycine dehydrogenase / decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Sarcosine oxidase, alpha subunit; Function of strongly homologous gene; enzyme. | 0.997 |
gcvP | soxB-3 | MexAM1_META1p0620 | MexAM1_META1p4108 | Glycine dehydrogenase / decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Sarcosine oxidase, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.929 |