STRINGSTRING
yhhF yhhF coaD coaD ACS41871.1 ACS41871.1 ACS40053.1 ACS40053.1 rlmH rlmH pyrH pyrH ACS41869.1 ACS41869.1 ACS41872.1 ACS41872.1 ftsY ftsY ACS39293.1 ACS39293.1 ACS41867.1 ACS41867.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
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[Homology]
Score
yhhFPutative methyltransferase with SAM-dependent methyltransferase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (184 aa)    
Predicted Functional Partners:
coaD
Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
  
 0.963
ACS41871.1
Conserved hypothetical protein with putative pseudouridine synthase-like domain; Homologs of previously reported genes of unknown function; Belongs to the pseudouridine synthase RsuA family.
     0.875
ACS40053.1
Conserved hypothetical protein, UPF0161 protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
  
    0.801
rlmH
Conserved hypothetical protein, UPF0247 protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
 
   
 0.620
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
 
   
 0.574
ACS41869.1
Putative oxidoreductase precursor, putative aldo/keto reductase precursor (tat pathway signal); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.570
ACS41872.1
Conserved hypothetical protein, DUF1328; Homologs of previously reported genes of unknown function.
       0.530
ftsY
Fused Signal Recognition Particle (SRP) receptor: membrane binding protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
 
   
 0.527
ACS39293.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
    0.512
ACS41867.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.503
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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