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tadA tadA tilS tilS ung ung hisE hisE purD purD ACS39580.1 ACS39580.1 ACS41148.1 ACS41148.1 ACS38693.1 ACS38693.1 ispE ispE ACS41879.1 ACS41879.1 pyrG pyrG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
tadAtRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (147 aa)    
Predicted Functional Partners:
tilS
tRNA(Ile)-lysidine synthase (tRNA(Ile)-lysidine synthetase, tRNA(Ile)-2-lysyl-cytidine synthase); Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
  
 0.872
ung
Uracil-DNA glycosylase (UDG); Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
 
 
 0.819
hisE
phosphoribosyl-ATP pyrophosphatase; Function of strongly homologous gene; enzyme.
   
  
 0.775
purD
Phosphoribosylglycinamide synthetase (GAR synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GARS family.
     
 0.759
ACS39580.1
Putative transcriptional coactivator/pterin dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
    0.695
ACS41148.1
Peptidase M22, glycoprotease; Function of strongly homologous gene; enzyme.
 
  
 0.680
ACS38693.1
Aloacid dehalogenase-like hydrolase; Function of strongly homologous gene; enzyme.
 
      0.677
ispE
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
    0.655
ACS41879.1
Putative short-chain dehydrogenase/reductase SDR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.588
pyrG
CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
 
    0.581
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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