node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS40062.1 | gid | MexAM1_META1p2276 | MexAM1_META1p4261 | Putative methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the methyltransferase superfamily. | tRNA uridine 5-carboxymethylaminomethyl modification enzyme gid; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | 0.608 |
ACS40062.1 | uppS | MexAM1_META1p2276 | MexAM1_META1p2070 | Putative methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the methyltransferase superfamily. | Undecaprenyl pyrophosphate synthetase (di-trans,poly-cis-decaprenylcistransferase); Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.454 |
ACS40062.1 | uppS-2 | MexAM1_META1p2276 | MexAM1_META1p4452 | Putative methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the methyltransferase superfamily. | Undecaprenyl pyrophosphate synthetase (di-trans,poly-cis-decaprenylcistransferase); Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.454 |
ACS41898.1 | gid | MexAM1_META1p4262 | MexAM1_META1p4261 | Conserved hypothetical protein, hemolysin-type calcium-binding repeat protein; Homologs of previously reported genes of unknown function. | tRNA uridine 5-carboxymethylaminomethyl modification enzyme gid; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | 0.458 |
argS | gid | MexAM1_META1p3624 | MexAM1_META1p4261 | arginyl-tRNA synthetase; Function of strongly homologous gene; enzyme. | tRNA uridine 5-carboxymethylaminomethyl modification enzyme gid; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | 0.564 |
argS | pnp | MexAM1_META1p3624 | MexAM1_META1p4416 | arginyl-tRNA synthetase; Function of strongly homologous gene; enzyme. | Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.772 |
argS | proS | MexAM1_META1p3624 | MexAM1_META1p0837 | arginyl-tRNA synthetase; Function of strongly homologous gene; enzyme. | proline-tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro); Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily. | 0.969 |
argS | pyrG | MexAM1_META1p3624 | MexAM1_META1p5110 | arginyl-tRNA synthetase; Function of strongly homologous gene; enzyme. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.856 |
gid | ACS40062.1 | MexAM1_META1p4261 | MexAM1_META1p2276 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme gid; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | Putative methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the methyltransferase superfamily. | 0.608 |
gid | ACS41898.1 | MexAM1_META1p4261 | MexAM1_META1p4262 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme gid; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | Conserved hypothetical protein, hemolysin-type calcium-binding repeat protein; Homologs of previously reported genes of unknown function. | 0.458 |
gid | argS | MexAM1_META1p4261 | MexAM1_META1p3624 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme gid; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | arginyl-tRNA synthetase; Function of strongly homologous gene; enzyme. | 0.564 |
gid | pnp | MexAM1_META1p4261 | MexAM1_META1p4416 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme gid; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.495 |
gid | proS | MexAM1_META1p4261 | MexAM1_META1p0837 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme gid; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | proline-tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro); Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily. | 0.569 |
gid | pyrG | MexAM1_META1p4261 | MexAM1_META1p5110 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme gid; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.570 |
gid | queA | MexAM1_META1p4261 | MexAM1_META1p3283 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme gid; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | S-adenosylmethionine:tRNA ribosyltransferase-isomerase (Queuosine biosynthesis protein queA); Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.794 |
gid | topA | MexAM1_META1p4261 | MexAM1_META1p3523 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme gid; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.464 |
gid | uppS | MexAM1_META1p4261 | MexAM1_META1p2070 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme gid; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | Undecaprenyl pyrophosphate synthetase (di-trans,poly-cis-decaprenylcistransferase); Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.769 |
gid | uppS-2 | MexAM1_META1p4261 | MexAM1_META1p4452 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme gid; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | Undecaprenyl pyrophosphate synthetase (di-trans,poly-cis-decaprenylcistransferase); Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.769 |
pnp | argS | MexAM1_META1p4416 | MexAM1_META1p3624 | Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | arginyl-tRNA synthetase; Function of strongly homologous gene; enzyme. | 0.772 |
pnp | gid | MexAM1_META1p4416 | MexAM1_META1p4261 | Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | tRNA uridine 5-carboxymethylaminomethyl modification enzyme gid; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | 0.495 |