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ubiH ubiH ubiG ubiG ubiE ubiE ACS39874.1 ACS39874.1 ubiA ubiA ubiB ubiB ACS37985.1 ACS37985.1 hemF hemF sdhB sdhB ACS40749.1 ACS40749.1 ACS42329.1 ACS42329.1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ubiH2-octaprenyl-6-methoxyphenol hydroxylase (FAD-dependent oxidoreductase); Function of strongly homologous gene; enzyme. (411 aa)    
Predicted Functional Partners:
ubiG
Putative UbiG: ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
 
 
 0.972
ubiE
Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).
  
 
 0.927
ACS39874.1
Putative ubiquinone biosynthesis hydroxylase/monooxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 
0.924
ubiA
P-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
  
   
 0.614
ubiB
Ubiquinone biosynthesis protein, putative 2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily.
  
 
 0.588
ACS37985.1
Glutaredoxin-like protein; Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the glutaredoxin family. Monothiol subfamily.
  
    0.553
hemF
Coproporphyrinogen III oxidase, aerobic (Coproporphyrinogenase) (Coprogen oxidase); Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
  
  
 0.552
sdhB
Succinate dehydrogenase, iron-sulfur subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
  
 0.538
ACS40749.1
Cyclase/dehydrase; Function of strongly homologous gene; enzyme.
  
   
 0.504
ACS42329.1
Glycine cleavage T protein (aminomethyl transferase); Function of strongly homologous gene; enzyme; Belongs to the GcvT family.
  
    0.488
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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