STRINGSTRING
ubiB ubiB ubiG ubiG coaBC coaBC ACS41945.1 ACS41945.1 ACS41944.1 ACS41944.1 ubiH ubiH fecE fecE ubiE ubiE ACS39874.1 ACS39874.1 ACS40749.1 ACS40749.1 ubiA ubiA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ubiBUbiquinone biosynthesis protein, putative 2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily. (521 aa)    
Predicted Functional Partners:
ubiG
Putative UbiG: ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
  
 0.755
coaBC
Coenzyme A biosynthesis bifunctional protein coaBC (DNA/pantothenate metabolism flavoprotein); Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
  
 0.655
ACS41945.1
Hypothetical protein; No homology to any previously reported sequences.
       0.639
ACS41944.1
Putative stabilisation protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
       0.626
ubiH
2-octaprenyl-6-methoxyphenol hydroxylase (FAD-dependent oxidoreductase); Function of strongly homologous gene; enzyme.
  
 
 0.588
fecE
Iron-dicitrate transporter subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter.
 
      0.534
ubiE
Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).
  
  
 0.523
ACS39874.1
Putative ubiquinone biosynthesis hydroxylase/monooxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.495
ACS40749.1
Cyclase/dehydrase; Function of strongly homologous gene; enzyme.
  
 
 
 0.456
ubiA
P-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
  
 
 
 0.426
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
Server load: low (10%) [HD]