node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS39874.1 | ACS40749.1 | MexAM1_META1p2074 | MexAM1_META1p3001 | Putative ubiquinone biosynthesis hydroxylase/monooxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Cyclase/dehydrase; Function of strongly homologous gene; enzyme. | 0.469 |
ACS39874.1 | ubiA | MexAM1_META1p2074 | MexAM1_META1p0666 | Putative ubiquinone biosynthesis hydroxylase/monooxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | P-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.595 |
ACS39874.1 | ubiB | MexAM1_META1p2074 | MexAM1_META1p4310 | Putative ubiquinone biosynthesis hydroxylase/monooxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Ubiquinone biosynthesis protein, putative 2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily. | 0.495 |
ACS39874.1 | ubiE | MexAM1_META1p2074 | MexAM1_META1p4311 | Putative ubiquinone biosynthesis hydroxylase/monooxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.929 |
ACS39874.1 | ubiG | MexAM1_META1p2074 | MexAM1_META1p0733 | Putative ubiquinone biosynthesis hydroxylase/monooxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative UbiG: ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.975 |
ACS39874.1 | ubiH | MexAM1_META1p2074 | MexAM1_META1p4277 | Putative ubiquinone biosynthesis hydroxylase/monooxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 2-octaprenyl-6-methoxyphenol hydroxylase (FAD-dependent oxidoreductase); Function of strongly homologous gene; enzyme. | 0.924 |
ACS40749.1 | ACS39874.1 | MexAM1_META1p3001 | MexAM1_META1p2074 | Cyclase/dehydrase; Function of strongly homologous gene; enzyme. | Putative ubiquinone biosynthesis hydroxylase/monooxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.469 |
ACS40749.1 | ubiA | MexAM1_META1p3001 | MexAM1_META1p0666 | Cyclase/dehydrase; Function of strongly homologous gene; enzyme. | P-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.599 |
ACS40749.1 | ubiB | MexAM1_META1p3001 | MexAM1_META1p4310 | Cyclase/dehydrase; Function of strongly homologous gene; enzyme. | Ubiquinone biosynthesis protein, putative 2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily. | 0.456 |
ACS40749.1 | ubiG | MexAM1_META1p3001 | MexAM1_META1p0733 | Cyclase/dehydrase; Function of strongly homologous gene; enzyme. | Putative UbiG: ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.737 |
ACS40749.1 | ubiH | MexAM1_META1p3001 | MexAM1_META1p4277 | Cyclase/dehydrase; Function of strongly homologous gene; enzyme. | 2-octaprenyl-6-methoxyphenol hydroxylase (FAD-dependent oxidoreductase); Function of strongly homologous gene; enzyme. | 0.504 |
ACS41944.1 | ACS41945.1 | MexAM1_META1p4308 | MexAM1_META1p4309 | Putative stabilisation protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Hypothetical protein; No homology to any previously reported sequences. | 0.781 |
ACS41944.1 | coaBC | MexAM1_META1p4308 | MexAM1_META1p4307 | Putative stabilisation protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Coenzyme A biosynthesis bifunctional protein coaBC (DNA/pantothenate metabolism flavoprotein); Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.576 |
ACS41944.1 | ubiB | MexAM1_META1p4308 | MexAM1_META1p4310 | Putative stabilisation protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Ubiquinone biosynthesis protein, putative 2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily. | 0.626 |
ACS41945.1 | ACS41944.1 | MexAM1_META1p4309 | MexAM1_META1p4308 | Hypothetical protein; No homology to any previously reported sequences. | Putative stabilisation protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.781 |
ACS41945.1 | coaBC | MexAM1_META1p4309 | MexAM1_META1p4307 | Hypothetical protein; No homology to any previously reported sequences. | Coenzyme A biosynthesis bifunctional protein coaBC (DNA/pantothenate metabolism flavoprotein); Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.564 |
ACS41945.1 | ubiB | MexAM1_META1p4309 | MexAM1_META1p4310 | Hypothetical protein; No homology to any previously reported sequences. | Ubiquinone biosynthesis protein, putative 2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily. | 0.639 |
coaBC | ACS41944.1 | MexAM1_META1p4307 | MexAM1_META1p4308 | Coenzyme A biosynthesis bifunctional protein coaBC (DNA/pantothenate metabolism flavoprotein); Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Putative stabilisation protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.576 |
coaBC | ACS41945.1 | MexAM1_META1p4307 | MexAM1_META1p4309 | Coenzyme A biosynthesis bifunctional protein coaBC (DNA/pantothenate metabolism flavoprotein); Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Hypothetical protein; No homology to any previously reported sequences. | 0.564 |
coaBC | ubiB | MexAM1_META1p4307 | MexAM1_META1p4310 | Coenzyme A biosynthesis bifunctional protein coaBC (DNA/pantothenate metabolism flavoprotein); Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Ubiquinone biosynthesis protein, putative 2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily. | 0.655 |