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ubiE ubiE ACS39874.1 ACS39874.1 ubiH ubiH ACS39489.1 ACS39489.1 ACS41010.1 ACS41010.1 ACS42042.1 ACS42042.1 wrbA wrbA ubiG ubiG ubiA ubiA lipA lipA ispB ispB
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ubiEUbiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (259 aa)    
Predicted Functional Partners:
ACS39874.1
Putative ubiquinone biosynthesis hydroxylase/monooxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.929
ubiH
2-octaprenyl-6-methoxyphenol hydroxylase (FAD-dependent oxidoreductase); Function of strongly homologous gene; enzyme.
  
 
 0.927
ACS39489.1
Putative NAD(P)H dehydrogenase (quione); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
  0.900
ACS41010.1
Putative NAD(P)H quinone oxidoreductasease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
  0.900
ACS42042.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
     
  0.900
wrbA
WrbA protein, flavodoxin-like domain, trp repressor-binding protein; Function of homologous gene experimentally demonstrated in an other organism; factor.
     
  0.900
ubiG
Putative UbiG: ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
  
 
 0.612
ubiA
P-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
 
   
 0.565
lipA
Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
 
   
 0.563
ispB
Octaprenyl diphosphate synthase; Function of strongly homologous gene; enzyme; Belongs to the FPP/GGPP synthase family.
 
  
 0.543
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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