node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS39489.1 | ACS41010.1 | MexAM1_META1p1640 | MexAM1_META1p3268 | Putative NAD(P)H dehydrogenase (quione); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative NAD(P)H quinone oxidoreductasease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.908 |
ACS39489.1 | ACS42042.1 | MexAM1_META1p1640 | MexAM1_META1p4411 | Putative NAD(P)H dehydrogenase (quione); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.902 |
ACS39489.1 | ubiE | MexAM1_META1p1640 | MexAM1_META1p4311 | Putative NAD(P)H dehydrogenase (quione); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.900 |
ACS39489.1 | wrbA | MexAM1_META1p1640 | MexAM1_META1p4676 | Putative NAD(P)H dehydrogenase (quione); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | WrbA protein, flavodoxin-like domain, trp repressor-binding protein; Function of homologous gene experimentally demonstrated in an other organism; factor. | 0.922 |
ACS39874.1 | ubiA | MexAM1_META1p2074 | MexAM1_META1p0666 | Putative ubiquinone biosynthesis hydroxylase/monooxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | P-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.595 |
ACS39874.1 | ubiE | MexAM1_META1p2074 | MexAM1_META1p4311 | Putative ubiquinone biosynthesis hydroxylase/monooxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.929 |
ACS39874.1 | ubiG | MexAM1_META1p2074 | MexAM1_META1p0733 | Putative ubiquinone biosynthesis hydroxylase/monooxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative UbiG: ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.975 |
ACS39874.1 | ubiH | MexAM1_META1p2074 | MexAM1_META1p4277 | Putative ubiquinone biosynthesis hydroxylase/monooxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 2-octaprenyl-6-methoxyphenol hydroxylase (FAD-dependent oxidoreductase); Function of strongly homologous gene; enzyme. | 0.924 |
ACS41010.1 | ACS39489.1 | MexAM1_META1p3268 | MexAM1_META1p1640 | Putative NAD(P)H quinone oxidoreductasease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative NAD(P)H dehydrogenase (quione); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.908 |
ACS41010.1 | ACS42042.1 | MexAM1_META1p3268 | MexAM1_META1p4411 | Putative NAD(P)H quinone oxidoreductasease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.902 |
ACS41010.1 | ubiE | MexAM1_META1p3268 | MexAM1_META1p4311 | Putative NAD(P)H quinone oxidoreductasease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.900 |
ACS41010.1 | wrbA | MexAM1_META1p3268 | MexAM1_META1p4676 | Putative NAD(P)H quinone oxidoreductasease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | WrbA protein, flavodoxin-like domain, trp repressor-binding protein; Function of homologous gene experimentally demonstrated in an other organism; factor. | 0.922 |
ACS42042.1 | ACS39489.1 | MexAM1_META1p4411 | MexAM1_META1p1640 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Putative NAD(P)H dehydrogenase (quione); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.902 |
ACS42042.1 | ACS41010.1 | MexAM1_META1p4411 | MexAM1_META1p3268 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Putative NAD(P)H quinone oxidoreductasease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.902 |
ACS42042.1 | ubiE | MexAM1_META1p4411 | MexAM1_META1p4311 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.900 |
ACS42042.1 | wrbA | MexAM1_META1p4411 | MexAM1_META1p4676 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | WrbA protein, flavodoxin-like domain, trp repressor-binding protein; Function of homologous gene experimentally demonstrated in an other organism; factor. | 0.901 |
ispB | ubiA | MexAM1_META1p3319 | MexAM1_META1p0666 | Octaprenyl diphosphate synthase; Function of strongly homologous gene; enzyme; Belongs to the FPP/GGPP synthase family. | P-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.913 |
ispB | ubiE | MexAM1_META1p3319 | MexAM1_META1p4311 | Octaprenyl diphosphate synthase; Function of strongly homologous gene; enzyme; Belongs to the FPP/GGPP synthase family. | Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.543 |
ispB | ubiH | MexAM1_META1p3319 | MexAM1_META1p4277 | Octaprenyl diphosphate synthase; Function of strongly homologous gene; enzyme; Belongs to the FPP/GGPP synthase family. | 2-octaprenyl-6-methoxyphenol hydroxylase (FAD-dependent oxidoreductase); Function of strongly homologous gene; enzyme. | 0.410 |
lipA | ubiE | MexAM1_META1p3000 | MexAM1_META1p4311 | Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.563 |