node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS41951.1 | purC | MexAM1_META1p4315 | MexAM1_META1p0412 | Colicin V-related production protein (membrane protein dedE-related) (putative Pur regulon protein); Function of strongly homologous gene; membrane component. | Phosphoribosylaminoimidazole-succinocarboxamide synthetase (SAICAR synthetase); Function of strongly homologous gene; enzyme; Belongs to the SAICAR synthetase family. | 0.840 |
ACS41951.1 | purD | MexAM1_META1p4315 | MexAM1_META1p4244 | Colicin V-related production protein (membrane protein dedE-related) (putative Pur regulon protein); Function of strongly homologous gene; membrane component. | Phosphoribosylglycinamide synthetase (GAR synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GARS family. | 0.736 |
ACS41951.1 | purE | MexAM1_META1p4315 | MexAM1_META1p1936 | Colicin V-related production protein (membrane protein dedE-related) (putative Pur regulon protein); Function of strongly homologous gene; membrane component. | Phosphoribosylaminoimidazole carboxylase = AIR carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.811 |
ACS41951.1 | purF | MexAM1_META1p4315 | MexAM1_META1p4314 | Colicin V-related production protein (membrane protein dedE-related) (putative Pur regulon protein); Function of strongly homologous gene; membrane component. | Amidophosphoribosyltransferase (PRPP amidotransferase); Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.893 |
ACS41951.1 | purH | MexAM1_META1p4315 | MexAM1_META1p2535 | Colicin V-related production protein (membrane protein dedE-related) (putative Pur regulon protein); Function of strongly homologous gene; membrane component. | Bifunctional: IMP cyclohydrolase (N-terminal); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.750 |
ACS41951.1 | purK | MexAM1_META1p4315 | MexAM1_META1p1937 | Colicin V-related production protein (membrane protein dedE-related) (putative Pur regulon protein); Function of strongly homologous gene; membrane component. | Phosphoribosylaminoimidazole carboxylase = AIR carboxylase, CO(2)-fixing subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.741 |
ACS41951.1 | purL | MexAM1_META1p4315 | MexAM1_META1p0010 | Colicin V-related production protein (membrane protein dedE-related) (putative Pur regulon protein); Function of strongly homologous gene; membrane component. | Phosphoribosylformylglycinamide synthetase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.799 |
ACS41951.1 | purM | MexAM1_META1p4315 | MexAM1_META1p2045 | Colicin V-related production protein (membrane protein dedE-related) (putative Pur regulon protein); Function of strongly homologous gene; membrane component. | Phosphoribosylaminoimidazole synthetase (AIR synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.823 |
ACS41951.1 | purN | MexAM1_META1p4315 | MexAM1_META1p2044 | Colicin V-related production protein (membrane protein dedE-related) (putative Pur regulon protein); Function of strongly homologous gene; membrane component. | Phosphoribosylglycinamide formyltransferase 1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.774 |
ACS41951.1 | purQ | MexAM1_META1p4315 | MexAM1_META1p0424 | Colicin V-related production protein (membrane protein dedE-related) (putative Pur regulon protein); Function of strongly homologous gene; membrane component. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.807 |
purC | ACS41951.1 | MexAM1_META1p0412 | MexAM1_META1p4315 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase (SAICAR synthetase); Function of strongly homologous gene; enzyme; Belongs to the SAICAR synthetase family. | Colicin V-related production protein (membrane protein dedE-related) (putative Pur regulon protein); Function of strongly homologous gene; membrane component. | 0.840 |
purC | purD | MexAM1_META1p0412 | MexAM1_META1p4244 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase (SAICAR synthetase); Function of strongly homologous gene; enzyme; Belongs to the SAICAR synthetase family. | Phosphoribosylglycinamide synthetase (GAR synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GARS family. | 0.951 |
purC | purE | MexAM1_META1p0412 | MexAM1_META1p1936 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase (SAICAR synthetase); Function of strongly homologous gene; enzyme; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazole carboxylase = AIR carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.997 |
purC | purF | MexAM1_META1p0412 | MexAM1_META1p4314 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase (SAICAR synthetase); Function of strongly homologous gene; enzyme; Belongs to the SAICAR synthetase family. | Amidophosphoribosyltransferase (PRPP amidotransferase); Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.968 |
purC | purH | MexAM1_META1p0412 | MexAM1_META1p2535 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase (SAICAR synthetase); Function of strongly homologous gene; enzyme; Belongs to the SAICAR synthetase family. | Bifunctional: IMP cyclohydrolase (N-terminal); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.960 |
purC | purK | MexAM1_META1p0412 | MexAM1_META1p1937 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase (SAICAR synthetase); Function of strongly homologous gene; enzyme; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazole carboxylase = AIR carboxylase, CO(2)-fixing subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.978 |
purC | purL | MexAM1_META1p0412 | MexAM1_META1p0010 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase (SAICAR synthetase); Function of strongly homologous gene; enzyme; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamide synthetase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.924 |
purC | purM | MexAM1_META1p0412 | MexAM1_META1p2045 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase (SAICAR synthetase); Function of strongly homologous gene; enzyme; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazole synthetase (AIR synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.953 |
purC | purN | MexAM1_META1p0412 | MexAM1_META1p2044 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase (SAICAR synthetase); Function of strongly homologous gene; enzyme; Belongs to the SAICAR synthetase family. | Phosphoribosylglycinamide formyltransferase 1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.947 |
purC | purQ | MexAM1_META1p0412 | MexAM1_META1p0424 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase (SAICAR synthetase); Function of strongly homologous gene; enzyme; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.930 |