node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS41964.1 | cspA-3 | MexAM1_META1p4329 | MexAM1_META1p4330 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Cold shock protein A; Function of homologous gene experimentally demonstrated in an other organism; factor. | 0.432 |
cspA-3 | ACS41964.1 | MexAM1_META1p4330 | MexAM1_META1p4329 | Cold shock protein A; Function of homologous gene experimentally demonstrated in an other organism; factor. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.432 |
cspA-3 | gap | MexAM1_META1p4330 | MexAM1_META1p2218 | Cold shock protein A; Function of homologous gene experimentally demonstrated in an other organism; factor. | Granule-associated 11 kDa protein; Function of homologous gene experimentally demonstrated in an other organism; factor. | 0.660 |
cspA-3 | hfq | MexAM1_META1p4330 | MexAM1_META1p3025 | Cold shock protein A; Function of homologous gene experimentally demonstrated in an other organism; factor. | Protein hfq, RNA-binding host factor; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.680 |
cspA-3 | lexA | MexAM1_META1p4330 | MexAM1_META1p5132 | Cold shock protein A; Function of homologous gene experimentally demonstrated in an other organism; factor. | SOS response transcriptional repressor, lexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.452 |
cspA-3 | rne | MexAM1_META1p4330 | MexAM1_META1p3916 | Cold shock protein A; Function of homologous gene experimentally demonstrated in an other organism; factor. | Putative ribonuclease E or G; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | 0.515 |
cspA-3 | rplT | MexAM1_META1p4330 | MexAM1_META1p1522 | Cold shock protein A; Function of homologous gene experimentally demonstrated in an other organism; factor. | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.433 |
cspA-3 | rpmE | MexAM1_META1p4330 | MexAM1_META1p2358 | Cold shock protein A; Function of homologous gene experimentally demonstrated in an other organism; factor. | 50S ribosomal protein L31; Function of strongly homologous gene; structure; Belongs to the bacterial ribosomal protein bL31 family. | 0.447 |
cspA-3 | rpoZ | MexAM1_META1p4330 | MexAM1_META1p3409 | Cold shock protein A; Function of homologous gene experimentally demonstrated in an other organism; factor. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.431 |
cspA-3 | rpsL | MexAM1_META1p4330 | MexAM1_META1p2148 | Cold shock protein A; Function of homologous gene experimentally demonstrated in an other organism; factor. | 30S ribosomal subunit protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. | 0.473 |
cspA-3 | sodB | MexAM1_META1p4330 | MexAM1_META1p3512 | Cold shock protein A; Function of homologous gene experimentally demonstrated in an other organism; factor. | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.478 |
gap | cspA-3 | MexAM1_META1p2218 | MexAM1_META1p4330 | Granule-associated 11 kDa protein; Function of homologous gene experimentally demonstrated in an other organism; factor. | Cold shock protein A; Function of homologous gene experimentally demonstrated in an other organism; factor. | 0.660 |
gap | hfq | MexAM1_META1p2218 | MexAM1_META1p3025 | Granule-associated 11 kDa protein; Function of homologous gene experimentally demonstrated in an other organism; factor. | Protein hfq, RNA-binding host factor; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.695 |
hfq | cspA-3 | MexAM1_META1p3025 | MexAM1_META1p4330 | Protein hfq, RNA-binding host factor; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Cold shock protein A; Function of homologous gene experimentally demonstrated in an other organism; factor. | 0.680 |
hfq | gap | MexAM1_META1p3025 | MexAM1_META1p2218 | Protein hfq, RNA-binding host factor; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Granule-associated 11 kDa protein; Function of homologous gene experimentally demonstrated in an other organism; factor. | 0.695 |
hfq | lexA | MexAM1_META1p3025 | MexAM1_META1p5132 | Protein hfq, RNA-binding host factor; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | SOS response transcriptional repressor, lexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.634 |
hfq | rne | MexAM1_META1p3025 | MexAM1_META1p3916 | Protein hfq, RNA-binding host factor; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Putative ribonuclease E or G; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | 0.801 |
hfq | rpsL | MexAM1_META1p3025 | MexAM1_META1p2148 | Protein hfq, RNA-binding host factor; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 30S ribosomal subunit protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. | 0.436 |
hfq | sodB | MexAM1_META1p3025 | MexAM1_META1p3512 | Protein hfq, RNA-binding host factor; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.593 |
lexA | cspA-3 | MexAM1_META1p5132 | MexAM1_META1p4330 | SOS response transcriptional repressor, lexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | Cold shock protein A; Function of homologous gene experimentally demonstrated in an other organism; factor. | 0.452 |