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bioB bioB bioD bioD bioA bioA ACS40861.1 ACS40861.1 ACS38762.1 ACS38762.1 bioF bioF hemA-2 hemA-2 hemA hemA rkpG rkpG queE queE moaA moaA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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bioBBiotin synthetase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (335 aa)    
Predicted Functional Partners:
bioD
Dethiobiotin synthetase (Dethiobiotin synthase) (DTB synthetase) (DTBS); Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 
 0.999
bioA
Adenosylmethionine---8-amino-7-oxononanoate aminotransferase; Function of strongly homologous gene; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.996
ACS40861.1
Putative aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.953
ACS38762.1
Putative biotin-protein ligase (birA-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.929
bioF
7-keto-8-aminopelargonic acid synthetase (8-amino-7-oxononanoate synthase; Function of strongly homologous gene; enzyme.
  
 0.829
hemA-2
5-aminolevulinic acid synthase (ALAS); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.783
hemA
5-aminolevulinic acid synthase (ALAS); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.771
rkpG
Acyltransferase (wcbT-like, rkpG-like); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.768
queE
Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
     
 0.757
moaA
Molybdenum biosynthetic protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
      
 0.755
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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