node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS38066.1 | ACS40557.1 | MexAM1_META1p0099 | MexAM1_META1p2804 | Excinuclease ABC, A subunit; Function of strongly homologous gene; enzyme. | UvrD/REP helicase; Function of strongly homologous gene; enzyme. | 0.493 |
ACS38066.1 | pheT | MexAM1_META1p0099 | MexAM1_META1p1524 | Excinuclease ABC, A subunit; Function of strongly homologous gene; enzyme. | Phenylalanine tRNA synthetase, beta-subunit; Function of strongly homologous gene; enzyme; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.440 |
ACS38066.1 | polA | MexAM1_META1p0099 | MexAM1_META1p2436 | Excinuclease ABC, A subunit; Function of strongly homologous gene; enzyme. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.565 |
ACS38066.1 | recA | MexAM1_META1p0099 | MexAM1_META1p2721 | Excinuclease ABC, A subunit; Function of strongly homologous gene; enzyme. | DNA strand exchange and recombination protein with protease and nuclease activity; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.603 |
ACS38066.1 | uvrA | MexAM1_META1p0099 | MexAM1_META1p4267 | Excinuclease ABC, A subunit; Function of strongly homologous gene; enzyme. | DNA excision repair enzyme subunit, with UvrBC; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.913 |
ACS38066.1 | uvrB | MexAM1_META1p0099 | MexAM1_META1p4445 | Excinuclease ABC, A subunit; Function of strongly homologous gene; enzyme. | UvrABC system protein B (UvrB protein) (Excinuclease ABC subunit B); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesi [...] | 0.988 |
ACS38066.1 | uvrC | MexAM1_META1p0099 | MexAM1_META1p3083 | Excinuclease ABC, A subunit; Function of strongly homologous gene; enzyme. | DNA exisiton repair enzyme together with UvrAB; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.791 |
ACS38066.1 | uvrD | MexAM1_META1p0099 | MexAM1_META1p0214 | Excinuclease ABC, A subunit; Function of strongly homologous gene; enzyme. | DNA-dependent ATPase I and helicase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.543 |
ACS39322.1 | polA | MexAM1_META1p1460 | MexAM1_META1p2436 | Hypothetical protein; No homology to any previously reported sequences. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.622 |
ACS39322.1 | recA | MexAM1_META1p1460 | MexAM1_META1p2721 | Hypothetical protein; No homology to any previously reported sequences. | DNA strand exchange and recombination protein with protease and nuclease activity; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.762 |
ACS39322.1 | uvrB | MexAM1_META1p1460 | MexAM1_META1p4445 | Hypothetical protein; No homology to any previously reported sequences. | UvrABC system protein B (UvrB protein) (Excinuclease ABC subunit B); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesi [...] | 0.735 |
ACS39322.1 | uvrC | MexAM1_META1p1460 | MexAM1_META1p3083 | Hypothetical protein; No homology to any previously reported sequences. | DNA exisiton repair enzyme together with UvrAB; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.645 |
ACS40557.1 | ACS38066.1 | MexAM1_META1p2804 | MexAM1_META1p0099 | UvrD/REP helicase; Function of strongly homologous gene; enzyme. | Excinuclease ABC, A subunit; Function of strongly homologous gene; enzyme. | 0.493 |
ACS40557.1 | polA | MexAM1_META1p2804 | MexAM1_META1p2436 | UvrD/REP helicase; Function of strongly homologous gene; enzyme. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.622 |
ACS40557.1 | recA | MexAM1_META1p2804 | MexAM1_META1p2721 | UvrD/REP helicase; Function of strongly homologous gene; enzyme. | DNA strand exchange and recombination protein with protease and nuclease activity; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.810 |
ACS40557.1 | uvrA | MexAM1_META1p2804 | MexAM1_META1p4267 | UvrD/REP helicase; Function of strongly homologous gene; enzyme. | DNA excision repair enzyme subunit, with UvrBC; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.475 |
ACS40557.1 | uvrB | MexAM1_META1p2804 | MexAM1_META1p4445 | UvrD/REP helicase; Function of strongly homologous gene; enzyme. | UvrABC system protein B (UvrB protein) (Excinuclease ABC subunit B); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesi [...] | 0.785 |
ACS40557.1 | uvrC | MexAM1_META1p2804 | MexAM1_META1p3083 | UvrD/REP helicase; Function of strongly homologous gene; enzyme. | DNA exisiton repair enzyme together with UvrAB; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.654 |
ACS40557.1 | uvrD | MexAM1_META1p2804 | MexAM1_META1p0214 | UvrD/REP helicase; Function of strongly homologous gene; enzyme. | DNA-dependent ATPase I and helicase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.911 |
clpP | uvrB | MexAM1_META1p2419 | MexAM1_META1p4445 | ATP-dependent Clp protease proteolytic subunit (Endopeptidase Clp); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | UvrABC system protein B (UvrB protein) (Excinuclease ABC subunit B); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesi [...] | 0.570 |