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glpK glpK glpD glpD ACS39958.1 ACS39958.1 plsY plsY ACS42085.1 ACS42085.1 aqpZ aqpZ aqpZ-2 aqpZ-2 ACS42089.1 ACS42089.1 gltA gltA ACS39035.1 ACS39035.1 ACS38270.1 ACS38270.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (501 aa)    
Predicted Functional Partners:
glpD
Sn-glycerol-3-phosphate dehydrogenase FAD/NAD(P)-binding (aerobic); Function of strongly homologous gene; enzyme; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
 0.999
ACS39958.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
   
 0.951
plsY
Putative 1-acyl glycerol-3-phosphate synthetase (PlsY); Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
    
 0.922
ACS42085.1
Conserved hypothetical protein, ankyrin repeat domain protein; Homologs of previously reported genes of unknown function.
   
 0.912
aqpZ
Water channel (aquaporin Z) (MIP family); Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
 
 0.870
aqpZ-2
Aquaporin; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
 
 0.870
ACS42089.1
Putative glycerophosphoryl diester phosphodiesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.853
gltA
Citrate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the citrate synthase family.
   
  
 0.800
ACS39035.1
Transcriptional regulator, DeoR family; Function of strongly homologous gene; putative regulator.
 
  
 0.717
ACS38270.1
Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
 
 
  
 0.708
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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