node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS42101.1 | gcvH | MexAM1_META1p4470 | MexAM1_META1p0621 | Putative dihydrolipoamide dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.973 |
ACS42101.1 | gcvP | MexAM1_META1p4470 | MexAM1_META1p0620 | Putative dihydrolipoamide dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Glycine dehydrogenase / decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.946 |
ACS42101.1 | gcvT | MexAM1_META1p4470 | MexAM1_META1p0622 | Putative dihydrolipoamide dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Glycine cleavage complex protein T, aminomethyltransferase, tetrahydrofolate-dependent; Function of strongly homologous gene; enzyme. | 0.942 |
ACS42101.1 | lpd | MexAM1_META1p4470 | MexAM1_META1p1542 | Putative dihydrolipoamide dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Dihydrolipoyl dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.928 |
ACS42101.1 | lpd-2 | MexAM1_META1p4470 | MexAM1_META1p2990 | Putative dihydrolipoamide dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Dihydrolipoamide dehydrogenase, E3 Component of Pyruvate dehydrogenase multienzyme complex; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.928 |
ACS42101.1 | pdhA | MexAM1_META1p4470 | MexAM1_META1p2986 | Putative dihydrolipoamide dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Pyruvate dehydrogenase E1 alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.990 |
ACS42101.1 | pdhB | MexAM1_META1p4470 | MexAM1_META1p2987 | Putative dihydrolipoamide dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.999 |
ACS42101.1 | pdhC | MexAM1_META1p4470 | MexAM1_META1p2989 | Putative dihydrolipoamide dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.992 |
ACS42101.1 | sucA | MexAM1_META1p4470 | MexAM1_META1p1540 | Putative dihydrolipoamide dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 2-oxoglutarate dehydrogenase complex, E1 component, 2-oxoglutarate decarboxylase, thiamine binding; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.982 |
ACS42101.1 | sucB | MexAM1_META1p4470 | MexAM1_META1p1541 | Putative dihydrolipoamide dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.990 |
gcvH | ACS42101.1 | MexAM1_META1p0621 | MexAM1_META1p4470 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Putative dihydrolipoamide dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.973 |
gcvH | gcvP | MexAM1_META1p0621 | MexAM1_META1p0620 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine dehydrogenase / decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |
gcvH | gcvT | MexAM1_META1p0621 | MexAM1_META1p0622 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage complex protein T, aminomethyltransferase, tetrahydrofolate-dependent; Function of strongly homologous gene; enzyme. | 0.999 |
gcvH | lpd | MexAM1_META1p0621 | MexAM1_META1p1542 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoyl dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.978 |
gcvH | lpd-2 | MexAM1_META1p0621 | MexAM1_META1p2990 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoamide dehydrogenase, E3 Component of Pyruvate dehydrogenase multienzyme complex; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.975 |
gcvH | pdhA | MexAM1_META1p0621 | MexAM1_META1p2986 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Pyruvate dehydrogenase E1 alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.765 |
gcvH | pdhB | MexAM1_META1p0621 | MexAM1_META1p2987 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.884 |
gcvH | pdhC | MexAM1_META1p0621 | MexAM1_META1p2989 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.638 |
gcvH | sucA | MexAM1_META1p0621 | MexAM1_META1p1540 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 2-oxoglutarate dehydrogenase complex, E1 component, 2-oxoglutarate decarboxylase, thiamine binding; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.869 |
gcvH | sucB | MexAM1_META1p0621 | MexAM1_META1p1541 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.638 |