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trmU trmU hemE hemE hppa hppa ribD ribD iscS iscS ribF ribF ygjD ygjD aspS aspS dnaG dnaG metF metF ACS42206.1 ACS42206.1
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gene co-occurrence
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textmining
co-expression
protein homology
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trmUtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (410 aa)    
Predicted Functional Partners:
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
      
 0.737
hppa
H+ translocating pyrophosphate synthase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.
     
 0.727
ribD
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
 
  
 0.653
iscS
Cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent; Function of strongly homologous gene; enzyme.
 
  
 0.653
ribF
Putative riboflavin biosynthesis protein ribF; Includes: Riboflavin kinase (Flavokinase); FMN adenylyltransferase (FAD pyrophosphorylase) (FAD synthetase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the ribF family.
 
    0.644
ygjD
O-sialoglycoprotein endopeptidase, with actin-like ATPase domain; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
 
   
 0.616
aspS
Aspartate tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
 
  
 0.592
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family.
 
    0.578
metF
5,10-methylenetetrahydrofolate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the methylenetetrahydrofolate reductase family.
     
 0.570
ACS42206.1
Putative metallo-dependent hydrolase, putative deoxyribonuclease, TatD family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
   0.561
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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