STRINGSTRING
emrB emrB ACS42123.1 ACS42123.1 mscL mscL cat cat zntA zntA proB proB proA proA ACS39979.1 ACS39979.1 ACS42135.1 ACS42135.1 ACS42124.1 ACS42124.1 ACS42811.1 ACS42811.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
emrBMultidrug efflux system protein; Function of strongly homologous gene; transporter; Belongs to the major facilitator superfamily. (525 aa)    
Predicted Functional Partners:
ACS42123.1
Putative multidrug resistance secretion protein (emrA-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
 0.971
mscL
Mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
   
  
 0.673
cat
Manganese catalase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.667
zntA
Zinc, cadmium, cobalt and lead efflux system; Function of strongly homologous gene; transporter.
      
 0.661
proB
Glutamate 5-kinase (Gamma-glutamyl kinase) (GK); Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
      
 0.661
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
      
 0.608
ACS39979.1
Hypothetical protein; No homology to any previously reported sequences.
  
     0.495
ACS42135.1
Hypothetical protein; No homology to any previously reported sequences.
  
     0.480
ACS42124.1
Transcriptional regulator, TetR family; Function of strongly homologous gene; regulator.
 
     0.451
ACS42811.1
Putative efflux pump component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component.
  
 
 0.422
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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