node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS40599.1 | ACS42280.1 | MexAM1_META1p2846 | MexAM1_META1p4651 | Putative 2-hydroxy-3-oxopropionate reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative pyridoxamine 5'-phosphate oxidase-related, FMN-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.606 |
ACS40599.1 | ribAB | MexAM1_META1p2846 | MexAM1_META1p3198 | Putative 2-hydroxy-3-oxopropionate reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 3,4-dihydroxy-2-butanone-4-phoshate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.404 |
ACS42280.1 | ACS40599.1 | MexAM1_META1p4651 | MexAM1_META1p2846 | Putative pyridoxamine 5'-phosphate oxidase-related, FMN-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative 2-hydroxy-3-oxopropionate reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.606 |
ACS42280.1 | ACS42281.1 | MexAM1_META1p4651 | MexAM1_META1p4652 | Putative pyridoxamine 5'-phosphate oxidase-related, FMN-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Hypothetical protein; No homology to any previously reported sequences. | 0.555 |
ACS42280.1 | ACS42742.1 | MexAM1_META1p4651 | MexAM1_META1p5138 | Putative pyridoxamine 5'-phosphate oxidase-related, FMN-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative oxidoreductase, aldo/keto reductase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.900 |
ACS42280.1 | gcvP | MexAM1_META1p4651 | MexAM1_META1p0620 | Putative pyridoxamine 5'-phosphate oxidase-related, FMN-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Glycine dehydrogenase / decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.413 |
ACS42280.1 | pdxH | MexAM1_META1p4651 | MexAM1_META1p4692 | Putative pyridoxamine 5'-phosphate oxidase-related, FMN-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Pyridoxine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.900 |
ACS42280.1 | pdxJ | MexAM1_META1p4651 | MexAM1_META1p2271 | Putative pyridoxamine 5'-phosphate oxidase-related, FMN-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Pyridoxal phosphate biosynthetic protein pdxJ (PNP synthase); Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.920 |
ACS42280.1 | pdxY | MexAM1_META1p4651 | MexAM1_META1p2863 | Putative pyridoxamine 5'-phosphate oxidase-related, FMN-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Pyridoxal kinase 2/pyridoxine kinase; Function of strongly homologous gene; enzyme; Belongs to the pyridoxine kinase family. | 0.921 |
ACS42280.1 | ribAB | MexAM1_META1p4651 | MexAM1_META1p3198 | Putative pyridoxamine 5'-phosphate oxidase-related, FMN-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 3,4-dihydroxy-2-butanone-4-phoshate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.442 |
ACS42281.1 | ACS42280.1 | MexAM1_META1p4652 | MexAM1_META1p4651 | Hypothetical protein; No homology to any previously reported sequences. | Putative pyridoxamine 5'-phosphate oxidase-related, FMN-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.555 |
ACS42742.1 | ACS42280.1 | MexAM1_META1p5138 | MexAM1_META1p4651 | Putative oxidoreductase, aldo/keto reductase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative pyridoxamine 5'-phosphate oxidase-related, FMN-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.900 |
ACS42742.1 | pdxH | MexAM1_META1p5138 | MexAM1_META1p4692 | Putative oxidoreductase, aldo/keto reductase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Pyridoxine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.901 |
ACS42742.1 | pdxY | MexAM1_META1p5138 | MexAM1_META1p2863 | Putative oxidoreductase, aldo/keto reductase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Pyridoxal kinase 2/pyridoxine kinase; Function of strongly homologous gene; enzyme; Belongs to the pyridoxine kinase family. | 0.903 |
gcvP | ACS42280.1 | MexAM1_META1p0620 | MexAM1_META1p4651 | Glycine dehydrogenase / decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Putative pyridoxamine 5'-phosphate oxidase-related, FMN-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.413 |
gcvP | pdxH | MexAM1_META1p0620 | MexAM1_META1p4692 | Glycine dehydrogenase / decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Pyridoxine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.413 |
pdxH | ACS42280.1 | MexAM1_META1p4692 | MexAM1_META1p4651 | Pyridoxine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Putative pyridoxamine 5'-phosphate oxidase-related, FMN-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.900 |
pdxH | ACS42742.1 | MexAM1_META1p4692 | MexAM1_META1p5138 | Pyridoxine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Putative oxidoreductase, aldo/keto reductase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.901 |
pdxH | gcvP | MexAM1_META1p4692 | MexAM1_META1p0620 | Pyridoxine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Glycine dehydrogenase / decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.413 |
pdxH | pdxJ | MexAM1_META1p4692 | MexAM1_META1p2271 | Pyridoxine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Pyridoxal phosphate biosynthetic protein pdxJ (PNP synthase); Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.936 |