STRINGSTRING
xerC xerC ftsK ftsK ftsK-2 ftsK-2 recR recR parB parB dnaA dnaA ACS38159.1 ACS38159.1 apt apt parA parA ACS42311.1 ACS42311.1 ACS42313.1 ACS42313.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xerCPtyrosine recombinase xerC, integrase/recombinase Ripx (xerC); Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (365 aa)    
Predicted Functional Partners:
ftsK
DNA-binding membrane protein required for chromosome resolution and partitioning; Function of strongly homologous gene; cell process.
  
   
 0.688
ftsK-2
Cell division protein; Function of strongly homologous gene; cell process; Belongs to the FtsK/SpoIIIE/SftA family.
  
   
 0.683
recR
Recombination protein recR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
  
   
 0.661
parB
Chromosome-partitioning protein parB; Function of strongly homologous gene; factor; Belongs to the ParB family.
  
  
 0.571
dnaA
DNA replication initiator protein, transcriptional regulator of replication and housekeeping genes; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
  
   
 0.568
ACS38159.1
Putative phosphoribosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
   
    0.566
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.560
parA
Chromosome partitioning protein, ATP-binding, nucleotide-binding; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
   
 0.541
ACS42311.1
Putative lactoylglutathione lyase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.536
ACS42313.1
Hypothetical protein; No homology to any previously reported sequences.
       0.526
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
Server load: low (20%) [HD]