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pdxH pdxH pdxJ pdxJ pdxY pdxY ACS42742.1 ACS42742.1 ACS42280.1 ACS42280.1 carB carB ACS42319.1 ACS42319.1 pyrB pyrB ribAB ribAB ACS42318.1 ACS42318.1 gcvP gcvP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
pdxHPyridoxine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (192 aa)    
Predicted Functional Partners:
pdxJ
Pyridoxal phosphate biosynthetic protein pdxJ (PNP synthase); Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
  
  
 0.936
pdxY
Pyridoxal kinase 2/pyridoxine kinase; Function of strongly homologous gene; enzyme; Belongs to the pyridoxine kinase family.
    
 0.921
ACS42742.1
Putative oxidoreductase, aldo/keto reductase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.901
ACS42280.1
Putative pyridoxamine 5'-phosphate oxidase-related, FMN-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
  0.900
carB
Carbamoyl phosphate synthase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarB family.
 
 
  
 0.618
ACS42319.1
Hypothetical protein; No homology to any previously reported sequences.
       0.570
pyrB
Aspartate carbamoyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
      0.512
ribAB
3,4-dihydroxy-2-butanone-4-phoshate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
  
  
 0.442
ACS42318.1
Chaperone DnaJ domain protein, putative heat shock protein; Function of strongly homologous gene; factor.
     
 0.432
gcvP
Glycine dehydrogenase / decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
 0.413
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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