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ACS42507.1 ACS42507.1 thiD thiD thiE-2 thiE-2 rsgA rsgA ACS39529.1 ACS39529.1 thiE thiE thiG thiG thiS thiS mxcE mxcE mxcQ mxcQ thiC thiC
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ACS42507.1Putative transcriptional activator (TenA family); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (227 aa)    
Predicted Functional Partners:
thiD
Bifunctional: hydroxy-methylpyrimidine kinase (HMP kinase); Function of strongly homologous gene; enzyme.
 
 0.999
thiE-2
Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
 0.935
rsgA
Putative GTPase; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
     
  0.900
ACS39529.1
Putative aminoglycoside phosphotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
  0.900
thiE
Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
 
  
 0.853
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.849
thiS
Thiamin biosynthesis proteinsulfur carrier) ThiS; Function of strongly homologous gene; factor.
  
    0.796
mxcE
Two component transcriptional regulator; Function of homologous gene experimentally demonstrated in an other organism; regulator.
       0.720
mxcQ
Integral membrane sensor signal transduction histidine kinase; Function of homologous gene experimentally demonstrated in an other organism; regulator.
       0.707
thiC
Thiamine biosynthesis protein thiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
  
 0.666
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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