node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS41198.1 | bacA | MexAM1_META1p3461 | MexAM1_META1p2389 | Conserved membrane hypothetical protein; Homologs of previously reported genes of unknown function. | Undecaprenyl-diphosphatase (Undecaprenyl pyrophosphate phosphatase) (Bacitracin resistance protein); Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.937 |
ACS41198.1 | mraY | MexAM1_META1p3461 | MexAM1_META1p5085 | Conserved membrane hypothetical protein; Homologs of previously reported genes of unknown function. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.906 |
bacA | ACS41198.1 | MexAM1_META1p2389 | MexAM1_META1p3461 | Undecaprenyl-diphosphatase (Undecaprenyl pyrophosphate phosphatase) (Bacitracin resistance protein); Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | Conserved membrane hypothetical protein; Homologs of previously reported genes of unknown function. | 0.937 |
bacA | mraY | MexAM1_META1p2389 | MexAM1_META1p5085 | Undecaprenyl-diphosphatase (Undecaprenyl pyrophosphate phosphatase) (Bacitracin resistance protein); Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.926 |
bacA | murD | MexAM1_META1p2389 | MexAM1_META1p5084 | Undecaprenyl-diphosphatase (Undecaprenyl pyrophosphate phosphatase) (Bacitracin resistance protein); Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.453 |
ddlB | ftsI | MexAM1_META1p3151 | MexAM1_META1p5088 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Peptidoglycan glycosyltransferase (penicillin-binding protein); Function of strongly homologous gene; enzyme. | 0.820 |
ddlB | ftsW | MexAM1_META1p3151 | MexAM1_META1p3146 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Cell division protein; Function of strongly homologous gene; cell process; Belongs to the SEDS family. | 0.967 |
ddlB | mraY | MexAM1_META1p3151 | MexAM1_META1p5085 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.946 |
ddlB | murC | MexAM1_META1p3151 | MexAM1_META1p3148 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.998 |
ddlB | murD | MexAM1_META1p3151 | MexAM1_META1p5084 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.961 |
ddlB | murE | MexAM1_META1p3151 | MexAM1_META1p5087 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.935 |
ddlB | murF | MexAM1_META1p3151 | MexAM1_META1p5086 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.998 |
ddlB | murG | MexAM1_META1p3151 | MexAM1_META1p3147 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.975 |
ftsI | ddlB | MexAM1_META1p5088 | MexAM1_META1p3151 | Peptidoglycan glycosyltransferase (penicillin-binding protein); Function of strongly homologous gene; enzyme. | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.820 |
ftsI | ftsW | MexAM1_META1p5088 | MexAM1_META1p3146 | Peptidoglycan glycosyltransferase (penicillin-binding protein); Function of strongly homologous gene; enzyme. | Cell division protein; Function of strongly homologous gene; cell process; Belongs to the SEDS family. | 0.969 |
ftsI | mraY | MexAM1_META1p5088 | MexAM1_META1p5085 | Peptidoglycan glycosyltransferase (penicillin-binding protein); Function of strongly homologous gene; enzyme. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.917 |
ftsI | murC | MexAM1_META1p5088 | MexAM1_META1p3148 | Peptidoglycan glycosyltransferase (penicillin-binding protein); Function of strongly homologous gene; enzyme. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.867 |
ftsI | murD | MexAM1_META1p5088 | MexAM1_META1p5084 | Peptidoglycan glycosyltransferase (penicillin-binding protein); Function of strongly homologous gene; enzyme. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.939 |
ftsI | murE | MexAM1_META1p5088 | MexAM1_META1p5087 | Peptidoglycan glycosyltransferase (penicillin-binding protein); Function of strongly homologous gene; enzyme. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.978 |
ftsI | murF | MexAM1_META1p5088 | MexAM1_META1p5086 | Peptidoglycan glycosyltransferase (penicillin-binding protein); Function of strongly homologous gene; enzyme. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.929 |