node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cobC | trpA | MexAM1_META1p5176 | MexAM1_META1p4890 | Threonine-phosphate decarboxylase (L-threonine-O-3- phosphate decarboxylase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Tryptophan synthase alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.833 |
cobC | trpB | MexAM1_META1p5176 | MexAM1_META1p0049 | Threonine-phosphate decarboxylase (L-threonine-O-3- phosphate decarboxylase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Tryptophan synthase, beta protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.520 |
cobC | trpD | MexAM1_META1p5176 | MexAM1_META1p5120 | Threonine-phosphate decarboxylase (L-threonine-O-3- phosphate decarboxylase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.812 |
hisC | trpA | MexAM1_META1p1486 | MexAM1_META1p4890 | Histidinol-phosphate aminotransferase; Function of strongly homologous gene; enzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Tryptophan synthase alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.834 |
hisC | trpB | MexAM1_META1p1486 | MexAM1_META1p0049 | Histidinol-phosphate aminotransferase; Function of strongly homologous gene; enzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Tryptophan synthase, beta protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.520 |
hisC | trpD | MexAM1_META1p1486 | MexAM1_META1p5120 | Histidinol-phosphate aminotransferase; Function of strongly homologous gene; enzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.812 |
pabA | pabB | MexAM1_META1p4283 | MexAM1_META1p4284 | Aminodeoxychorismate synthase subunit II, component of p-aminobenzoate synthase multienzyme complex; Function of strongly homologous gene; enzyme. | Para-aminobenzoate synthase component I (ADC synthase); Function experimentally demonstrated in the studied strain; enzyme. | 0.999 |
pabA | trpA | MexAM1_META1p4283 | MexAM1_META1p4890 | Aminodeoxychorismate synthase subunit II, component of p-aminobenzoate synthase multienzyme complex; Function of strongly homologous gene; enzyme. | Tryptophan synthase alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.966 |
pabA | trpB | MexAM1_META1p4283 | MexAM1_META1p0049 | Aminodeoxychorismate synthase subunit II, component of p-aminobenzoate synthase multienzyme complex; Function of strongly homologous gene; enzyme. | Tryptophan synthase, beta protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.956 |
pabA | trpC | MexAM1_META1p4283 | MexAM1_META1p5121 | Aminodeoxychorismate synthase subunit II, component of p-aminobenzoate synthase multienzyme complex; Function of strongly homologous gene; enzyme. | Indole-3-glycerol phosphate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TrpC family. | 0.996 |
pabA | trpD | MexAM1_META1p4283 | MexAM1_META1p5120 | Aminodeoxychorismate synthase subunit II, component of p-aminobenzoate synthase multienzyme complex; Function of strongly homologous gene; enzyme. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.998 |
pabA | trpE | MexAM1_META1p4283 | MexAM1_META1p5117 | Aminodeoxychorismate synthase subunit II, component of p-aminobenzoate synthase multienzyme complex; Function of strongly homologous gene; enzyme. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.999 |
pabA | trpF | MexAM1_META1p4283 | MexAM1_META1p0050 | Aminodeoxychorismate synthase subunit II, component of p-aminobenzoate synthase multienzyme complex; Function of strongly homologous gene; enzyme. | Putative phosphoribosylanthranilate isomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the TrpF family. | 0.963 |
pabA | trpG | MexAM1_META1p4283 | MexAM1_META1p5119 | Aminodeoxychorismate synthase subunit II, component of p-aminobenzoate synthase multienzyme complex; Function of strongly homologous gene; enzyme. | Aminodeoxychorismate synthase component II, Glutamine amido-transferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.810 |
pabB | pabA | MexAM1_META1p4284 | MexAM1_META1p4283 | Para-aminobenzoate synthase component I (ADC synthase); Function experimentally demonstrated in the studied strain; enzyme. | Aminodeoxychorismate synthase subunit II, component of p-aminobenzoate synthase multienzyme complex; Function of strongly homologous gene; enzyme. | 0.999 |
pabB | trpA | MexAM1_META1p4284 | MexAM1_META1p4890 | Para-aminobenzoate synthase component I (ADC synthase); Function experimentally demonstrated in the studied strain; enzyme. | Tryptophan synthase alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.986 |
pabB | trpB | MexAM1_META1p4284 | MexAM1_META1p0049 | Para-aminobenzoate synthase component I (ADC synthase); Function experimentally demonstrated in the studied strain; enzyme. | Tryptophan synthase, beta protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.958 |
pabB | trpC | MexAM1_META1p4284 | MexAM1_META1p5121 | Para-aminobenzoate synthase component I (ADC synthase); Function experimentally demonstrated in the studied strain; enzyme. | Indole-3-glycerol phosphate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TrpC family. | 0.990 |
pabB | trpD | MexAM1_META1p4284 | MexAM1_META1p5120 | Para-aminobenzoate synthase component I (ADC synthase); Function experimentally demonstrated in the studied strain; enzyme. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.994 |
pabB | trpE | MexAM1_META1p4284 | MexAM1_META1p5117 | Para-aminobenzoate synthase component I (ADC synthase); Function experimentally demonstrated in the studied strain; enzyme. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.836 |