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phoU phoU pstA pstA pstB pstB pstC pstC ACS40801.1 ACS40801.1 pstS pstS phoB phoB hppa hppa minE minE crtI crtI ppk ppk
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
phoUNegative regulator of PhoR/PhoB two-component regulator; Plays a role in the regulation of phosphate uptake. (237 aa)    
Predicted Functional Partners:
pstA
Phosphate ABC transporter, permease; Function of strongly homologous gene; transporter.
  
 0.986
pstB
Phosphate ABC transporter, ATPase; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
  
 0.986
pstC
Phosphate ABC transporter, permease; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
  
 0.892
ACS40801.1
ABC transporter related ATP-binding protein, putative molybdate/tungstate transporter; Function of strongly homologous gene; transporter; Belongs to the ABC transporter superfamily.
  
 0.881
pstS
Phosphate ABC transporter, periplasmic phosphate binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.
 
  
 0.875
phoB
Phosphate regulon transcriptional regulatory protein PhoB; Function of homologous gene experimentally demonstrated in an other organism; regulator.
  
 0.823
hppa
H+ translocating pyrophosphate synthase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.
      
 0.660
minE
Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
  
    0.613
crtI
Phytoene dehydrogenase (phytoene desaturase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.607
ppk
Polyphosphate kinase, component of RNA degradosome; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.
     
 0.605
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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