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pssA pssA psd psd pgsA pgsA cdsA cdsA ACS40601.1 ACS40601.1 ilvA ilvA trpB trpB sga sga glyA glyA sdaB sdaB sga-2 sga-2
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
pssAPhosphatidylserine synthase (pssA-like); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (280 aa)    
Predicted Functional Partners:
psd
Phosphatidylserine decarboxylase (psd-like); Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
 
 
 0.993
pgsA
Phosphatidylglycerophosphate synthetase; Function of strongly homologous gene; enzyme; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
 
 0.957
cdsA
CDP-diglyceride synthase; Function of strongly homologous gene; enzyme; Belongs to the CDS family.
    
 0.932
ACS40601.1
Putative phosphoserine phosphatase (serB-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
    
  0.910
ilvA
Threonine deaminase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
    
  0.901
trpB
Tryptophan synthase, beta protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
  0.900
sga
Serine-glyoxylate aminotransferase (SGAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
     
  0.900
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.900
sdaB
L-serine deaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
  0.900
sga-2
Serine-glyoxylate aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
  0.900
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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