STRINGSTRING
cysS cysS cysE cysE cysE-2 cysE-2 cysK cysK serS serS tpiA tpiA hisS hisS leuS leuS cysK-2 cysK-2 thrS thrS rrm rrm
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysSCysteine tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. (462 aa)    
Predicted Functional Partners:
cysE
Serine acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.958
cysE-2
Serine acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.940
cysK
Subunit of cysteine synthase A and O-acetylserine sulfhydrolase A, PLP-dependent enzyme; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.926
serS
Serine tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
 
 
 0.803
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 
  
 0.794
hisS
histidyl-tRNA synthetase; Function of strongly homologous gene; enzyme.
  
  
 0.783
leuS
Leucine tRNA synthetase; Function of strongly homologous gene; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 0.776
cysK-2
Cysteine synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.772
thrS
Threonine tRNA synthetase; Function of strongly homologous gene; enzyme; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
  
 0.752
rrm
rRNA methylase; Function of strongly homologous gene; enzyme; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
 
 
 0.737
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.