node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS41896.1 | tilS | MexAM1_META1p4260 | MexAM1_META1p5300 | UDP-N-acetylglucosamine 2-epimerase-like protein (fragment); Gene remnant; enzyme. | tRNA(Ile)-lysidine synthase (tRNA(Ile)-lysidine synthetase, tRNA(Ile)-2-lysyl-cytidine synthase); Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.669 |
cpoB | ftsH | MexAM1_META1p5301 | MexAM1_META1p5299 | Conserved hypothetical protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. | Cell division protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.562 |
cpoB | tilS | MexAM1_META1p5301 | MexAM1_META1p5300 | Conserved hypothetical protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. | tRNA(Ile)-lysidine synthase (tRNA(Ile)-lysidine synthetase, tRNA(Ile)-2-lysyl-cytidine synthase); Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.847 |
engA | pth | MexAM1_META1p4433 | MexAM1_META1p2439 | GTP-binding protein EngA, GTPase; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Peptidyl-tRNA hydrolase (PTH); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.467 |
engA | tilS | MexAM1_META1p4433 | MexAM1_META1p5300 | GTP-binding protein EngA, GTPase; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | tRNA(Ile)-lysidine synthase (tRNA(Ile)-lysidine synthetase, tRNA(Ile)-2-lysyl-cytidine synthase); Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.676 |
ftsH | cpoB | MexAM1_META1p5299 | MexAM1_META1p5301 | Cell division protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Conserved hypothetical protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. | 0.562 |
ftsH | hpt | MexAM1_META1p5299 | MexAM1_META1p3063 | Cell division protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Hypoxanthine phosphoribosyl transferase; Function of strongly homologous gene; enzyme; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.869 |
ftsH | tilS | MexAM1_META1p5299 | MexAM1_META1p5300 | Cell division protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | tRNA(Ile)-lysidine synthase (tRNA(Ile)-lysidine synthetase, tRNA(Ile)-2-lysyl-cytidine synthase); Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.748 |
hpt | ftsH | MexAM1_META1p3063 | MexAM1_META1p5299 | Hypoxanthine phosphoribosyl transferase; Function of strongly homologous gene; enzyme; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Cell division protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.869 |
hpt | tilS | MexAM1_META1p3063 | MexAM1_META1p5300 | Hypoxanthine phosphoribosyl transferase; Function of strongly homologous gene; enzyme; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | tRNA(Ile)-lysidine synthase (tRNA(Ile)-lysidine synthetase, tRNA(Ile)-2-lysyl-cytidine synthase); Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.945 |
mfd | mfd-2 | MexAM1_META1p4552 | MexAM1_META1p1061 | Transcription repair coupling protein, ATP-dependent helicase; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | DEAD/DEAH box helicase domain protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.913 |
mfd | pth | MexAM1_META1p4552 | MexAM1_META1p2439 | Transcription repair coupling protein, ATP-dependent helicase; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Peptidyl-tRNA hydrolase (PTH); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.759 |
mfd | tilS | MexAM1_META1p4552 | MexAM1_META1p5300 | Transcription repair coupling protein, ATP-dependent helicase; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | tRNA(Ile)-lysidine synthase (tRNA(Ile)-lysidine synthetase, tRNA(Ile)-2-lysyl-cytidine synthase); Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.705 |
mfd-2 | mfd | MexAM1_META1p1061 | MexAM1_META1p4552 | DEAD/DEAH box helicase domain protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Transcription repair coupling protein, ATP-dependent helicase; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.913 |
mfd-2 | pth | MexAM1_META1p1061 | MexAM1_META1p2439 | DEAD/DEAH box helicase domain protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Peptidyl-tRNA hydrolase (PTH); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.759 |
mfd-2 | tilS | MexAM1_META1p1061 | MexAM1_META1p5300 | DEAD/DEAH box helicase domain protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | tRNA(Ile)-lysidine synthase (tRNA(Ile)-lysidine synthetase, tRNA(Ile)-2-lysyl-cytidine synthase); Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.710 |
pth | engA | MexAM1_META1p2439 | MexAM1_META1p4433 | Peptidyl-tRNA hydrolase (PTH); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | GTP-binding protein EngA, GTPase; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.467 |
pth | mfd | MexAM1_META1p2439 | MexAM1_META1p4552 | Peptidyl-tRNA hydrolase (PTH); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | Transcription repair coupling protein, ATP-dependent helicase; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.759 |
pth | mfd-2 | MexAM1_META1p2439 | MexAM1_META1p1061 | Peptidyl-tRNA hydrolase (PTH); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | DEAD/DEAH box helicase domain protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.759 |
pth | tilS | MexAM1_META1p2439 | MexAM1_META1p5300 | Peptidyl-tRNA hydrolase (PTH); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | tRNA(Ile)-lysidine synthase (tRNA(Ile)-lysidine synthetase, tRNA(Ile)-2-lysyl-cytidine synthase); Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.867 |