STRINGSTRING
rpn15 rpn15 rpn3 rpn3 rpn8 rpn8 rpn10 rpn10 rpn11 rpn11 rpn12 rpn12 rpn7 rpn7 rpn6 rpn6 rpn9 rpn9 rpt1 rpt1 rpt3 rpt3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpn1526S proteasome complex subunit rpn15; Versatile protein that might stabilize multiple protein complexes involved in diverse pathways. Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis. Acts as a ubiquitin receptor of the 26S proteasome, by interacting with ubiquitin chains linked by 'Lys-63' and 'Lys-48'. Involved in nuclear export of specific sets of mRNAs. Links the mRNA adapter mlo3 to rae1 for targeting mRNA-protein complex to the proteins of the nucleoporin complex (NPC). Involved in recombinational repair of DNA. Plays a critical role in linking [...] (71 aa)    
Predicted Functional Partners:
rpn3
Probable 26S proteasome regulatory subunit rpn3; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
   
 0.999
rpn8
26S proteasome regulatory subunit rpn8; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
   
 0.999
rpn10
26S proteasome regulatory subunit rpn10; Protects ubiquitin chains against dissambly by deubiquitinating enzymes thereby promoting protein degradation.
   
 0.999
rpn11
26S proteasome regulatory subunit rpn11; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
   
 0.999
rpn12
26S proteasome regulatory subunit rpn12; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
   
 0.999
rpn7
Probable 26S proteasome regulatory subunit rpn7; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
   
 0.999
rpn6
Probable 26S proteasome regulatory subunit rpn6; Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, rpn6 is required for proteasome assembly (By similarity); Belongs to the proteasome subunit S9 family.
   
 0.999
rpn9
Probable 26S proteasome regulatory subunit rpn9; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
   
 0.999
rpt1
26S proteasome regulatory subunit 7 homolog; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity).
   
 0.998
rpt3
26S proteasome regulatory subunit 6B homolog; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity).
   
 0.998
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.