STRINGSTRING
opm opm bai bai eca eca CG16903 CG16903 CG9706 CG9706 CG1965 CG1965 wntD wntD CG11999 CG11999 CG31678 CG31678 wg wg GCS2alpha GCS2alpha
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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opmOpossum, isoform A; Opossum (opm) encodes a p24 protein that contributes to the secretion of Wnt ligands; Belongs to the EMP24/GP25L family. (242 aa)    
Predicted Functional Partners:
bai
Transmembrane emp24 domain-containing protein bai; Eca and bai are essential, though not redundant, for dorsoventral patterning of the embryo. Specifically required during early embryogenesis for the activity of maternal tkv, while the zygotic tkv is not affected; Belongs to the EMP24/GP25L family.
   
 
 0.921
eca
Transmembrane emp24 domain-containing protein eca; Eca and bai are essential, though not redundant, for dorsoventral patterning of the embryo. Specifically required during early embryogenesis for the activity of maternal tkv, while the zygotic tkv is not affected. Involved in Golgi organization. Belongs to the EMP24/GP25L family.
    
 
 0.829
CG16903
LD24704p; Cyclin-dependent protein serine/threonine kinase regulator activity. It is involved in the biological process described with: regulation of transcription by RNA polymerase II.
   
  
 0.714
CG9706
Uncharacterized protein, isoform C; Solute:proton symporter activity; acetyl-CoA transmembrane transporter activity.
   
  
 0.680
CG1965
LD29489p; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity. It is involved in the biological process described with: mRNA splicing, via spliceosome; negative regulation of transcription by RNA polymerase II.
      
 0.664
wntD
Wnt inhibitor of Dorsal protein; Binds as a ligand to a family of frizzled seven-transmembrane receptors and acts through a cascade of genes on the nucleus. Belongs to the Wnt family.
   
 
 0.663
CG11999
GH21273p; Dolichyl-phosphate-mannose-protein mannosyltransferase activity. It is involved in the biological process described with: ER-associated misfolded protein catabolic process; protein O-linked mannosylation.
   
 
 0.630
CG31678
LD18032p.
   
  
 0.617
wg
Protein wingless; Binds as a ligand to a family of frizzled seven-transmembrane receptors and acts through a cascade of genes on the nucleus. Segment polarity protein. May be a growth factor. Acts on neighboring cells to regulate at least one gene, the homeobox segmentation gene engrailed. Wg signal represses arm phosphorylation. Wg signaling operates by inactivating the sgg repression of engrailed autoactivation. Wg and Wnt2 have a role in the developing trachea and together are responsible for all dorsal trunk formation. Wg also acts in the developing epidermis. Acts as a morphogen, [...]
   
 0.615
GCS2alpha
Glucan 1,3-alpha-glucosidase activity; carbohydrate binding. It is involved in the biological process described with: carbohydrate metabolic process; Belongs to the glycosyl hydrolase 31 family.
      
 0.604
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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