node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PA0874 | phhR | PA0874 | PA0873 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Transcriptional regulator PhhR; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.882 |
aroP1 | dhcA | PA3000 | PA1999 | Aromatic amino acid transport protein AroP1; Product name confidence: Class 2 (High similarity to functionally studied protein). | DhcA, dehydrocarnitine CoA transferase, subunit A; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | 0.755 |
aroP1 | hpd | PA3000 | PA0865 | Aromatic amino acid transport protein AroP1; Product name confidence: Class 2 (High similarity to functionally studied protein). | 4-hydroxyphenylpyruvate dioxygenase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the 4HPPD family. | 0.504 |
aroP1 | pheA | PA3000 | PA3166 | Aromatic amino acid transport protein AroP1; Product name confidence: Class 2 (High similarity to functionally studied protein). | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate. | 0.488 |
aroP1 | phhR | PA3000 | PA0873 | Aromatic amino acid transport protein AroP1; Product name confidence: Class 2 (High similarity to functionally studied protein). | Transcriptional regulator PhhR; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.595 |
dhcA | aroP1 | PA1999 | PA3000 | DhcA, dehydrocarnitine CoA transferase, subunit A; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | Aromatic amino acid transport protein AroP1; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.755 |
dhcA | hmgA | PA1999 | PA2009 | DhcA, dehydrocarnitine CoA transferase, subunit A; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. | 0.641 |
dhcA | hpd | PA1999 | PA0865 | DhcA, dehydrocarnitine CoA transferase, subunit A; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | 4-hydroxyphenylpyruvate dioxygenase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the 4HPPD family. | 0.665 |
dhcA | phhR | PA1999 | PA0873 | DhcA, dehydrocarnitine CoA transferase, subunit A; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | Transcriptional regulator PhhR; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.693 |
hmgA | dhcA | PA2009 | PA1999 | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. | DhcA, dehydrocarnitine CoA transferase, subunit A; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | 0.641 |
hmgA | hpd | PA2009 | PA0865 | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. | 4-hydroxyphenylpyruvate dioxygenase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the 4HPPD family. | 0.999 |
hmgA | pheA | PA2009 | PA3166 | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate. | 0.400 |
hmgA | phhA | PA2009 | PA0872 | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. | Phenylalanine-4-hydroxylase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. | 0.991 |
hmgA | phhB | PA2009 | PA0871 | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. | Pterin-4-alpha-carbinolamine dehydratase; Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. May also have a positive regulatory role in the expression of phhA. | 0.921 |
hmgA | phhC | PA2009 | PA0870 | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. | Aromatic amino acid aminotransferase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | 0.924 |
hmgA | phhR | PA2009 | PA0873 | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. | Transcriptional regulator PhhR; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.807 |
hpd | aroP1 | PA0865 | PA3000 | 4-hydroxyphenylpyruvate dioxygenase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the 4HPPD family. | Aromatic amino acid transport protein AroP1; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.504 |
hpd | dhcA | PA0865 | PA1999 | 4-hydroxyphenylpyruvate dioxygenase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the 4HPPD family. | DhcA, dehydrocarnitine CoA transferase, subunit A; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | 0.665 |
hpd | hmgA | PA0865 | PA2009 | 4-hydroxyphenylpyruvate dioxygenase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the 4HPPD family. | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. | 0.999 |
hpd | pheA | PA0865 | PA3166 | 4-hydroxyphenylpyruvate dioxygenase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the 4HPPD family. | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate. | 0.441 |