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There are several matches for 'PA1169'.
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organism
protein
1)
Pseudomonas aeruginosa
loxA - Probable lipoxygenase; Exhibits lipoxin synthase activity as part of a bacterial evasion strategy to suppress the host immune defense. Oxygenates polyenoic fatty acids including eicosatrienoate and docosahexaenoate to the corresponding (n-6)S-hydroperoxy derivatives. In turn, this production of bioactive lipid mediators promotes bacterial persistence in host lung tissues by inhibiting the expression of major chemokines and recruitment of leukocytes.
[a.k.a.
PA1169
, AAG04558.1, NZ_QZGE01000006.1]
2)
Nocardia seriolae
loxA - Arachidonate 15-lipoxygenase; Converts arachidonic acid to 15S- hydroperoxyeicosatetraenoic acid (HpETE) which is rapidly reduced to hydroxyeicosatetraenoic acid (HETE). Could act on exogenous human-derived substrates to potentially modulate the local inflammatory responses during P. aeruginosa infections; Belongs to the lipoxygenase family; Contains 1 lipoxygenase domain; KEGG: pae:
PA1169
arachidonate 15-lipoxygenase.
[a.k.a. NS506_06256, APB00292.1, NZ_BBYQ01000040.1]