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oprH oprH phoP phoP phoQ phoQ oprF oprF oprG oprG oprE oprE oprC oprC PA1343 PA1343 oprD oprD napC napC PA1053 PA1053
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
oprHPhoP/Q and low Mg2+ inducible outer membrane protein H1 precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (200 aa)    
Predicted Functional Partners:
phoP
Two-component response regulator PhoP; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
 0.993
phoQ
Two-component sensor PhoQ; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
 0.991
oprF
Major porin and structural outer membrane porin OprF precursor; Has porin activity, forming small water-filled channels. Also has a structural role in determining cell shape and ability to grow in low-osmolarity medium; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
  
 
 0.962
oprG
Outer membrane protein OprG precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
 0.930
oprE
Anaerobically-induced outer membrane porin OprE precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
      
 0.898
oprC
Putative copper transport outer membrane porin OprC precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
      
 0.873
PA1343
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
   
  
 0.857
oprD
Basic amino acid, basic peptide and imipenem outer membrane porin OprD precursor; Porin with a specificity for basic amino acids. Also possesses serine protease activity; Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.
   
  
 0.849
napC
Cytochrome c-type protein NapC; Product name confidence: Class 2 (High similarity to functionally studied protein).
  
 
 0.837
PA1053
Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
   
  
 0.806
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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