node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PA4130 | PA4513 | PA4130 | PA4513 | Probable sulfite or nitrite reductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Probable oxidoreductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.997 |
PA4130 | cysA | PA4130 | PA0280 | Probable sulfite or nitrite reductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Sulfate transport protein CysA; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. | 0.776 |
PA4130 | cysC | PA4130 | PA1393 | Probable sulfite or nitrite reductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Adenosine 5'-phosphosulfate (APS) kinase; Catalyzes the synthesis of activated sulfate. | 0.791 |
PA4130 | cysD | PA4130 | PA4443 | Probable sulfite or nitrite reductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | ATP sulfurylase small subunit; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.820 |
PA4130 | cysG | PA4130 | PA2611 | Probable sulfite or nitrite reductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.916 |
PA4130 | cysH | PA4130 | PA1756 | Probable sulfite or nitrite reductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 3'-phosphoadenosine-5'-phosphosulfate reductase; Reduction of activated sulfate into sulfite; Belongs to the PAPS reductase family. CysH subfamily. | 0.993 |
PA4130 | cysI | PA4130 | PA1838 | Probable sulfite or nitrite reductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Sulfite reductase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.902 |
PA4130 | cysN | PA4130 | PA4442 | Probable sulfite or nitrite reductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | ATP sulfurylase GTP-binding subunit/APS kinase; ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity; In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.958 |
PA4130 | cysW | PA4130 | PA0281 | Probable sulfite or nitrite reductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Sulfate transport protein CysW; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.831 |
PA4513 | PA4130 | PA4513 | PA4130 | Probable oxidoreductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Probable sulfite or nitrite reductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.997 |
PA4513 | cysA | PA4513 | PA0280 | Probable oxidoreductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Sulfate transport protein CysA; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. | 0.941 |
PA4513 | cysC | PA4513 | PA1393 | Probable oxidoreductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Adenosine 5'-phosphosulfate (APS) kinase; Catalyzes the synthesis of activated sulfate. | 0.835 |
PA4513 | cysD | PA4513 | PA4443 | Probable oxidoreductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | ATP sulfurylase small subunit; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.748 |
PA4513 | cysG | PA4513 | PA2611 | Probable oxidoreductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.793 |
PA4513 | cysH | PA4513 | PA1756 | Probable oxidoreductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 3'-phosphoadenosine-5'-phosphosulfate reductase; Reduction of activated sulfate into sulfite; Belongs to the PAPS reductase family. CysH subfamily. | 0.973 |
PA4513 | cysI | PA4513 | PA1838 | Probable oxidoreductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Sulfite reductase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.990 |
PA4513 | cysN | PA4513 | PA4442 | Probable oxidoreductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | ATP sulfurylase GTP-binding subunit/APS kinase; ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity; In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.969 |
PA4513 | cysW | PA4513 | PA0281 | Probable oxidoreductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Sulfate transport protein CysW; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.901 |
cysA | PA4130 | PA0280 | PA4130 | Sulfate transport protein CysA; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. | Probable sulfite or nitrite reductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.776 |
cysA | PA4513 | PA0280 | PA4513 | Sulfate transport protein CysA; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. | Probable oxidoreductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.941 |