node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Maqu_1208 | Maqu_2006 | Maqu_1208 | Maqu_2006 | SOS response UmuD protein, Serine peptidase, MEROPS family S24; PFAM: peptidase S24, S26A and S26B; KEGG: abo:ABO_1583 LexA repressor; Belongs to the peptidase S24 family. | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | 0.619 |
Maqu_1208 | Maqu_2961 | Maqu_1208 | Maqu_2961 | SOS response UmuD protein, Serine peptidase, MEROPS family S24; PFAM: peptidase S24, S26A and S26B; KEGG: abo:ABO_1583 LexA repressor; Belongs to the peptidase S24 family. | KEGG: pau:PA14_19950 hypothetical protein. | 0.650 |
Maqu_1208 | Maqu_3364 | Maqu_1208 | Maqu_3364 | SOS response UmuD protein, Serine peptidase, MEROPS family S24; PFAM: peptidase S24, S26A and S26B; KEGG: abo:ABO_1583 LexA repressor; Belongs to the peptidase S24 family. | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.658 |
Maqu_1208 | recA | Maqu_1208 | Maqu_2082 | SOS response UmuD protein, Serine peptidase, MEROPS family S24; PFAM: peptidase S24, S26A and S26B; KEGG: abo:ABO_1583 LexA repressor; Belongs to the peptidase S24 family. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.942 |
Maqu_2006 | Maqu_1208 | Maqu_2006 | Maqu_1208 | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | SOS response UmuD protein, Serine peptidase, MEROPS family S24; PFAM: peptidase S24, S26A and S26B; KEGG: abo:ABO_1583 LexA repressor; Belongs to the peptidase S24 family. | 0.619 |
Maqu_2006 | Maqu_2961 | Maqu_2006 | Maqu_2961 | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | KEGG: pau:PA14_19950 hypothetical protein. | 0.792 |
Maqu_2006 | Maqu_3364 | Maqu_2006 | Maqu_3364 | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.835 |
Maqu_2006 | lexA | Maqu_2006 | Maqu_2007 | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.912 |
Maqu_2006 | recA | Maqu_2006 | Maqu_2082 | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.605 |
Maqu_2006 | ruvA | Maqu_2006 | Maqu_1705 | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | Holliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.408 |
Maqu_2960 | Maqu_2961 | Maqu_2960 | Maqu_2961 | KEGG: abo:ABO_0143 hypothetical protein. | KEGG: pau:PA14_19950 hypothetical protein. | 0.506 |
Maqu_2961 | Maqu_1208 | Maqu_2961 | Maqu_1208 | KEGG: pau:PA14_19950 hypothetical protein. | SOS response UmuD protein, Serine peptidase, MEROPS family S24; PFAM: peptidase S24, S26A and S26B; KEGG: abo:ABO_1583 LexA repressor; Belongs to the peptidase S24 family. | 0.650 |
Maqu_2961 | Maqu_2006 | Maqu_2961 | Maqu_2006 | KEGG: pau:PA14_19950 hypothetical protein. | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | 0.792 |
Maqu_2961 | Maqu_2960 | Maqu_2961 | Maqu_2960 | KEGG: pau:PA14_19950 hypothetical protein. | KEGG: abo:ABO_0143 hypothetical protein. | 0.506 |
Maqu_2961 | Maqu_3364 | Maqu_2961 | Maqu_3364 | KEGG: pau:PA14_19950 hypothetical protein. | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.561 |
Maqu_2961 | lexA | Maqu_2961 | Maqu_2007 | KEGG: pau:PA14_19950 hypothetical protein. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.650 |
Maqu_2961 | recA | Maqu_2961 | Maqu_2082 | KEGG: pau:PA14_19950 hypothetical protein. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.524 |
Maqu_2961 | ruvA | Maqu_2961 | Maqu_1705 | KEGG: pau:PA14_19950 hypothetical protein. | Holliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.405 |
Maqu_3364 | Maqu_1208 | Maqu_3364 | Maqu_1208 | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | SOS response UmuD protein, Serine peptidase, MEROPS family S24; PFAM: peptidase S24, S26A and S26B; KEGG: abo:ABO_1583 LexA repressor; Belongs to the peptidase S24 family. | 0.658 |
Maqu_3364 | Maqu_2006 | Maqu_3364 | Maqu_2006 | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | 0.835 |