STRINGSTRING
trpF trpF trpC trpC trpD trpD Htur_0513 Htur_0513 trpE trpE Htur_2139 Htur_2139 trpA trpA trpB-2 trpB-2 trpB trpB Htur_1366 Htur_1366 Htur_1365 Htur_1365
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpFPFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: pau:PA14_23850 N-(5'- phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (216 aa)    
Predicted Functional Partners:
trpC
PFAM: Indole-3-glycerol phosphate synthase; KEGG: lhk:LHK_01448 TrpC; Belongs to the TrpC family.
 
 0.999
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 
 0.999
Htur_0513
PFAM: glycosyl transferase family 3; KEGG: tcx:Tcr_0268 anthranilate phosphoribosyltransferase.
 
 
 0.993
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
 
  
 0.988
Htur_2139
TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: sml:Smlt4311 anthranilate synthase component II.
 
  
 0.987
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
  
 0.983
trpB-2
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 0.924
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 0.917
Htur_1366
KEGG: gme:Gmet_2497 anthranilate synthase, component I; TIGRFAM: para-aminobenzoate synthase component I; PFAM: Chorismate binding-like; Anthranilate synthase component I domain protein.
 
  
 0.917
Htur_1365
TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: mei:Msip34_2513 glutamine amidotransferase of anthranilate synthase.
 
  
 0.910
Your Current Organism:
Haloterrigena turkmenica
NCBI taxonomy Id: 543526
Other names: H. turkmenica DSM 5511, Haloterrigena turkmenica ATCC 51198, Haloterrigena turkmenica DSM 5511, Haloterrigena turkmenica str. DSM 5511, Haloterrigena turkmenica strain DSM 5511
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.