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Tcur_1565 Tcur_1565 ilvD ilvD Tcur_0296 Tcur_0296 Tcur_0396 Tcur_0396 Tcur_2046 Tcur_2046 Tcur_3543 Tcur_3543 argJ argJ leuA leuA Tcur_3542 Tcur_3542 Tcur_3131 Tcur_3131 Tcur_4011 Tcur_4011
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Tcur_1565PFAM: aminotransferase class I and II; KEGG: pau:PA14_27500 aminotransferase AlaT. (404 aa)    
Predicted Functional Partners:
ilvD
KEGG: nmn:NMCC_1068 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
  
 
 0.918
Tcur_0296
PFAM: Glu/Leu/Phe/Val dehydrogenase dimerisation region; Glu/Leu/Phe/Val dehydrogenase; KEGG: sml:Smlt3523 putative valine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.909
Tcur_0396
Glutamate dehydrogenase (NADP(+)); PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: ank:AnaeK_3118 glutamate dehydrogenase (NADP(+)); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.909
Tcur_2046
PFAM: aminotransferase class IV; KEGG: hch:HCH_06836 branched-chain amino acid aminotransferase.
  
 
 0.909
Tcur_3543
TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV; KEGG: rhi:NGR_c35490 branched-chain-amino-acid aminotransferase.
  
 
 0.909
argJ
Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
    
 0.908
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 
 0.908
Tcur_3542
TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: LeuA allosteric (dimerisation) domain; pyruvate carboxyltransferase; KEGG: scl:sce3734 putative alpha- isopropylmalate/homocitrate synthase family transferase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.908
Tcur_3131
TIGRFAM: alanine dehydrogenase; PFAM: alanine dehydrogenase/PNT domain protein; KEGG: csa:Csal_2966 L-alanine dehydrogenase; Belongs to the AlaDH/PNT family.
     
 0.906
Tcur_4011
PFAM: NAD-glutamate dehydrogenase; KEGG: tmz:Tmz1t_1660 NAD-glutamate dehydrogenase.
     
 0.903
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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