STRINGSTRING
Pden_1183 Pden_1183 Pden_0240 Pden_0240 Pden_3435 Pden_3435 Pden_4400 Pden_4400 Pden_2929 Pden_2929 Pden_1106 Pden_1106 Pden_1184 Pden_1184 Pden_1185 Pden_1185
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Pden_1183Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: pau:PA14_47820 putative transcriptional regulator. (226 aa)    
Predicted Functional Partners:
Pden_0240
Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: mes:Meso_4461 transcriptional regulator, GntR family.
  
     0.774
Pden_3435
Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: rsp:RSP_3445 transcriptional regulator, GntR family.
  
     0.774
Pden_4400
Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein; Helix-turn-helix, type 11 domain protein; KEGG: rru:Rru_A1414 regulatory protein GntR.
  
  
 0.758
Pden_2929
Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein; Helix-turn-helix, type 11 domain protein; KEGG: mag:amb0238 transcriptional regulator.
  
  
 0.757
Pden_1106
Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: sil:SPO1912 transcriptional regulator, GntR family.
  
  
 0.691
Pden_1184
Proline racemase; Catalyzes the dehydration of trans-3-hydroxy-L-proline (t3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C). Is likely involved in a degradation pathway that converts t3LHyp to L-proline, which would allow P.denitrificans to grow on t3LHyp as a sole carbon source. Displays neither proline racemase activity nor 4-hydroxyproline 2-epimerase activity.
       0.494
Pden_1185
Ornithine cyclodeaminase; Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using preferentially NADPH over NADH as the electron donor. Is likely involved in a degradation pathway that converts trans-3-hydroxy-L-proline (t3LHyp) to L-proline, which would allow P.denitrificans to grow on t3LHyp as a sole carbon source. Belongs to the ornithine cyclodeaminase/mu-crystallin family.
       0.469
Your Current Organism:
Paracoccus denitrificans
NCBI taxonomy Id: 318586
Other names: P. denitrificans PD1222, Paracoccus denitrificans PD1222
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