node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
gltA | nuoD | PA1580 | PA2639 | Citrate synthase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | NADH dehydrogenase I chain C,D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.845 |
gltA | prpC | PA1580 | PA0795 | Citrate synthase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Citrate synthase 2; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the citrate synthase family. | 0.849 |
gltA | sdhA | PA1580 | PA1583 | Citrate synthase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Succinate dehydrogenase (A subunit); Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.886 |
gltA | sdhB | PA1580 | PA1584 | Citrate synthase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Succinate dehydrogenase (B subunit); Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.931 |
gltA | sdhC | PA1580 | PA1581 | Citrate synthase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Succinate dehydrogenase (C subunit); Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.910 |
gltA | sdhD | PA1580 | PA1582 | Citrate synthase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Succinate dehydrogenase (D subunit); Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.795 |
gltA | sucA | PA1580 | PA1585 | Citrate synthase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 2-oxoglutarate dehydrogenase (E1 subunit); Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.980 |
gltA | sucB | PA1580 | PA1586 | Citrate synthase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Dihydrolipoamide succinyltransferase (E2 subunit); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.875 |
gltA | sucC | PA1580 | PA1588 | Citrate synthase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. Can also generate UTP or CTP, although it preferentially synthesizes ATP and/or GTP. | 0.992 |
gltA | sucD | PA1580 | PA1589 | Citrate synthase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. Can also generate UTP or CTP, although it preferentially synthesizes ATP and/or GTP. | 0.954 |
nuoD | gltA | PA2639 | PA1580 | NADH dehydrogenase I chain C,D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | Citrate synthase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.845 |
nuoD | prpC | PA2639 | PA0795 | NADH dehydrogenase I chain C,D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | Citrate synthase 2; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the citrate synthase family. | 0.817 |
nuoD | sdhA | PA2639 | PA1583 | NADH dehydrogenase I chain C,D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | Succinate dehydrogenase (A subunit); Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.973 |
nuoD | sdhB | PA2639 | PA1584 | NADH dehydrogenase I chain C,D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | Succinate dehydrogenase (B subunit); Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.983 |
nuoD | sdhC | PA2639 | PA1581 | NADH dehydrogenase I chain C,D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | Succinate dehydrogenase (C subunit); Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.970 |
nuoD | sdhD | PA2639 | PA1582 | NADH dehydrogenase I chain C,D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | Succinate dehydrogenase (D subunit); Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.918 |
nuoD | sucA | PA2639 | PA1585 | NADH dehydrogenase I chain C,D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 2-oxoglutarate dehydrogenase (E1 subunit); Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.965 |
nuoD | sucB | PA2639 | PA1586 | NADH dehydrogenase I chain C,D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | Dihydrolipoamide succinyltransferase (E2 subunit); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.725 |
nuoD | sucC | PA2639 | PA1588 | NADH dehydrogenase I chain C,D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. Can also generate UTP or CTP, although it preferentially synthesizes ATP and/or GTP. | 0.970 |
nuoD | sucD | PA2639 | PA1589 | NADH dehydrogenase I chain C,D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. Can also generate UTP or CTP, although it preferentially synthesizes ATP and/or GTP. | 0.964 |