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exsB exsB exsC exsC exsE exsE exsA exsA exsD exsD pcrV pcrV popB popB pscE pscE popD popD exoS exoS pcrH pcrH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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exsBExoenzyme S synthesis protein B; Involved in the synthesis of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Pilot protein that is required for the proper localization of the secretin PscC in the outer membrane. Necessary for full in vivo virulence ; Belongs to the ExsB/YscW family. (137 aa)    
Predicted Functional Partners:
exsC
ExsC, exoenzyme S synthesis protein C precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
 0.992
exsE
ExsE; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
 0.991
exsA
Transcriptional regulator ExsA; Appears to be required for induction of exoenzyme S synthesis above a low basal level.
  
  
 0.988
exsD
ExsD; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
 0.948
pcrV
Type III secretion protein PcrV; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
 0.939
popB
Translocator protein PopB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
 0.915
pscE
Type III export protein PscE; Prevents premature polymerization of PscF, along with PscG, within the cytoplasm. Required for type III secretion needle assembly. Also required for cytotoxicity by influencing PscF levels. Belongs to the YscE family.
  
  
 0.914
popD
Translocator outer membrane protein PopD precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
 0.911
exoS
Exoenzyme S; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
   
  
 0.906
pcrH
Regulatory protein PcrH; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
 0.875
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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