STRINGSTRING
exsD exsD exsA exsA exsC exsC pscC pscC pscB pscB exoT exoT exsE exsE pscG pscG exsB exsB pscI pscI pcrV pcrV
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
exsDExsD; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (276 aa)    
Predicted Functional Partners:
exsA
Transcriptional regulator ExsA; Appears to be required for induction of exoenzyme S synthesis above a low basal level.
  
 
 0.998
exsC
ExsC, exoenzyme S synthesis protein C precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
 
 0.996
pscC
Type III secretion outer membrane protein PscC precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
 0.974
pscB
Type III export apparatus protein; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
 0.973
exoT
Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
   
  
 0.967
exsE
ExsE; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
 0.966
pscG
Type III export protein PscG; Prevents premature polymerization of PscF, along with PscE, within the cytoplasm. Required for type III secretion needle assembly. Also required for cytotoxicity by influencing PscF levels.
  
  
 0.950
exsB
Exoenzyme S synthesis protein B; Involved in the synthesis of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Pilot protein that is required for the proper localization of the secretin PscC in the outer membrane. Necessary for full in vivo virulence ; Belongs to the ExsB/YscW family.
  
  
 0.948
pscI
Type III export protein PscI; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
 0.946
pcrV
Type III secretion protein PcrV; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
 0.945
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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