node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PA1772 | cmaX | PA1772 | PA1773 | Probable methyltransferase; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity). | CmaX protein; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.844 |
PA1772 | cmpX | PA1772 | PA1775 | Probable methyltransferase; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity). | Conserved cytoplasmic membrane protein, CmpX protein; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.832 |
PA1772 | crfX | PA1772 | PA1774 | Probable methyltransferase; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity). | CrfX protein; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | 0.467 |
PA1772 | sigX | PA1772 | PA1776 | Probable methyltransferase; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity). | ECF sigma factor SigX; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the sigma-70 factor family. ECF subfamily. | 0.619 |
cmaX | PA1772 | PA1773 | PA1772 | CmaX protein; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Probable methyltransferase; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity). | 0.844 |
cmaX | cmpX | PA1773 | PA1775 | CmaX protein; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Conserved cytoplasmic membrane protein, CmpX protein; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.917 |
cmaX | crfX | PA1773 | PA1774 | CmaX protein; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | CrfX protein; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | 0.650 |
cmaX | oprF | PA1773 | PA1777 | CmaX protein; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Major porin and structural outer membrane porin OprF precursor; Has porin activity, forming small water-filled channels. Also has a structural role in determining cell shape and ability to grow in low-osmolarity medium; Belongs to the outer membrane OOP (TC 1.B.6) superfamily. | 0.591 |
cmaX | sigX | PA1773 | PA1776 | CmaX protein; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | ECF sigma factor SigX; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the sigma-70 factor family. ECF subfamily. | 0.822 |
cmpX | PA1772 | PA1775 | PA1772 | Conserved cytoplasmic membrane protein, CmpX protein; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Probable methyltransferase; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity). | 0.832 |
cmpX | cmaX | PA1775 | PA1773 | Conserved cytoplasmic membrane protein, CmpX protein; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | CmaX protein; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.917 |
cmpX | crfX | PA1775 | PA1774 | Conserved cytoplasmic membrane protein, CmpX protein; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | CrfX protein; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | 0.987 |
cmpX | fabY | PA1775 | PA5174 | Conserved cytoplasmic membrane protein, CmpX protein; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Probable beta-ketoacyl synthase; Involved in the initiation of the fatty acid biosynthesis. Catalyzes the condensation of acetyl coenzyme A (acetyl-CoA) with malonyl-acyl carrier protein (ACP) to make the fatty acid synthesis (FAS) primer beta-acetoacetyl-ACP. It can also use short-chain acyl-CoA as substrates, including butyryl-CoA, and hexanoyl-CoA, but does not use any of the longer chain acyl-CoA substrates. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.709 |
cmpX | oprF | PA1775 | PA1777 | Conserved cytoplasmic membrane protein, CmpX protein; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Major porin and structural outer membrane porin OprF precursor; Has porin activity, forming small water-filled channels. Also has a structural role in determining cell shape and ability to grow in low-osmolarity medium; Belongs to the outer membrane OOP (TC 1.B.6) superfamily. | 0.955 |
cmpX | sigX | PA1775 | PA1776 | Conserved cytoplasmic membrane protein, CmpX protein; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | ECF sigma factor SigX; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the sigma-70 factor family. ECF subfamily. | 0.980 |
crfX | PA1772 | PA1774 | PA1772 | CrfX protein; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | Probable methyltransferase; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity). | 0.467 |
crfX | cmaX | PA1774 | PA1773 | CrfX protein; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | CmaX protein; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.650 |
crfX | cmpX | PA1774 | PA1775 | CrfX protein; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | Conserved cytoplasmic membrane protein, CmpX protein; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.987 |
crfX | fabY | PA1774 | PA5174 | CrfX protein; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | Probable beta-ketoacyl synthase; Involved in the initiation of the fatty acid biosynthesis. Catalyzes the condensation of acetyl coenzyme A (acetyl-CoA) with malonyl-acyl carrier protein (ACP) to make the fatty acid synthesis (FAS) primer beta-acetoacetyl-ACP. It can also use short-chain acyl-CoA as substrates, including butyryl-CoA, and hexanoyl-CoA, but does not use any of the longer chain acyl-CoA substrates. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.439 |
crfX | oprF | PA1774 | PA1777 | CrfX protein; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | Major porin and structural outer membrane porin OprF precursor; Has porin activity, forming small water-filled channels. Also has a structural role in determining cell shape and ability to grow in low-osmolarity medium; Belongs to the outer membrane OOP (TC 1.B.6) superfamily. | 0.503 |