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nhaB nhaB nhaP2 nhaP2 nhaP nhaP nqrA nqrA sotB sotB PA5529 PA5529 kefB kefB bpt bpt nqrB nqrB fimL fimL PA1821 PA1821
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
nhaBSodium/proton antiporter NhaB; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. Can also transport lithium. Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family. (500 aa)    
Predicted Functional Partners:
nhaP2
Probable sodium/hydrogen antiporter; K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
   
  
 0.893
nhaP
Na+/H+ antiporter NhaP; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. Has also weak Li(+)/H(+) antiport activity. Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
   
  
 0.889
nqrA
Na+-translocating NADH:ubiquinone oxidoreductase subunit Nrq1; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
   
  
 0.766
sotB
Probable major facilitator superfamily (MFS) transporter; Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites; Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.
      
 0.593
PA5529
Probable sodium/proton antiporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
      
 0.523
kefB
Glutathione-regulated potassium-efflux system protein KefB; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
   
  
 0.518
bpt
Hypothetical protein; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily.
      
 0.493
nqrB
Na+-translocating NADH:ubiquinone oxidoreductase subunit Nrq2; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
   
  
 0.481
fimL
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
  
    0.480
PA1821
Probable enoyl-CoA hydratase/isomerase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the enoyl-CoA hydratase/isomerase family.
  
    0.478
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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